Macitentan

  • Catalog number
    B1856-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]-N'- propylsulfamide;  ACT-064992
  • Description
    Macitentan is an orally active endothelin receptor antagonist (ERA) approved for the treatment of pulmonary arterial hypertension (PAH).
  • CAS Number
    441798-33-0
  • Structure Available
    Yes
  • Molecular Formula
    C₁₉H₂₀Br₂N₆O₄S
  • Molecular Weight
    588.27
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    An orally active endothelin receptor antagonist (ERA)
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • PubChem CID
    16004692
  • SMILES
    CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br
  • InChi
    InChI=1S/C19H20Br2N6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-15(21)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27)
  • InChi Key
    JGCMEBMXRHSZKX-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Macitentan
  • Alternative name
    Macitentan
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