Macitentan
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Catalog numberB1856-5
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PricePlease ask
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Size5 mg
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Alternative_nameN-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]-N'- propylsulfamide; ACT-064992
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DescriptionMacitentan is an orally active endothelin receptor antagonist (ERA) approved for the treatment of pulmonary arterial hypertension (PAH).
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CAS Number441798-33-0
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Structure AvailableYes
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Molecular FormulaC₁₉H₂₀Br₂N₆O₄S
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Molecular Weight588.27
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineAn orally active endothelin receptor antagonist (ERA)
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID16004692
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SMILESCCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br
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InChiInChI=1S/C19H20Br2N6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-15(21)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27)
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InChi KeyJGCMEBMXRHSZKX-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameMacitentan
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Alternative nameMacitentan
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