Recombinant Signaling Threshold Regulating Transmembrane Adaptor 1 (SIT1)

• Catalog number
  RPH166Ra01
• Price
  Please ask
• Size
  456

• Source
  Prokaryotic expression
• Predicted Molecular Mass KD
  22.8kDa
• Accurate Molecular Mass KD
  NA
• Organism species
  Rattus norvegicus (Rat)
• Item Name
  Signaling Threshold Regulating Transmembrane Adaptor 1
• Alternative Names
  SIT; Suppression Inducing Transmembrane adaptor 1; SHP2 Interacting Transmembrane Adaptor
• Research Area
  Signal transduction;
• Buffer Formulation
  PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Traits
  Freeze-dried powder
• Isoelectric Point
  6.4
• Purity
  ≥ 95%
• Protein length
  Ser2~Pro175
• Tag
  two N-terminal Tags, His-tag and T7-tag
• Expression System
  Prokaryotic expression
• Application
  Positive Control; Immunogen; SDS-PAGE; WB.
• Manual link
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants
• Description
  Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.

• Gene target
  Signaling   Threshold   Regulating   Transmembrane   Adaptor   SIT1  
• Gene symbol
  SIT1, SLC6A20
• Short name
  Recombinant Signaling Threshold Regulating Transmembrane Adaptor 1 (SIT1)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Cloud Clone Corp advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  E.coli
• Species
  Rattus norvegicus (Rat)
• Alternative name
  Rec. Signaling Threshold Regulating Transmembrane Adaptor 1 (signaling threshold regulating transmembrane adaptor 1)
• Alternative technique
  rec
• Alternative to gene target
  signaling threshold regulating transmembrane adaptor 1, SIT1 and IDBG-62762 and ENSG00000137078 and 27240, SH2 domain binding, Plasma membranes, Sit1 and IDBG-141175 and ENSMUSG00000028460 and 54390, SIT1 and IDBG-633050 and ENSBTAG00000011411 and 512027

Gene info

• Identity
  HGNC:17710
• Gene
  SIT1
• Long gene name
  signaling threshold regulating transmembrane adaptor 1
• Synonyms gene name
  • suppression inducing transmembrane adaptor 1
• Synonyms
  • SIT
• Synonyms name
  • SHP2 interacting transmembrane adaptor
• Locus
  9p13.3
• Discovery year
  2005-04-25
• Entrez gene record
  27240
• Pubmed identfication
  • 11491537
  • 10209036
• RefSeq identity
  • NM_014450
• VEGA ID
  OTTHUMG00000019867

Gene info

• Identity
  HGNC:30927
• Gene
  SLC6A20
• Long gene name
  solute carrier family 6 member 20
• Synonyms gene name
  • solute carrier family 6 (proline IMINO transporter), member 20
• Synonyms
  • XT3
  • Xtrp3
  • SIT1
  • IMINO
• Synonyms name
  • sodium-dependent imino acid transporter 1
• GenBank acession
  • AF075260
• Locus
  3p21.31
• Discovery year
  2004-04-02
• Entrez gene record
  54716
• Pubmed identfication
  • 9932288
  • 11352561
• RefSeq identity
  • NM_020208
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000133446

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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