Human CellExp™ LILRB2, human recombinant

• Catalog number
  P1147-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  LILRB2, ILT4, LIR2, MIR10, CD85d
• Alternative_names
  LILRB2, ILT4, LIR2, MIR10, CD85d
• Description
  Receptor for class I MHC antigens
• Recombinant
  Yes
• Source
  HEK 293 cells
• Purity by SDS PAGE
  > 85%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per/ug
• Molecular Weight
  74.4 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
• Reconstitution Instructions
  Reconstitute in sterile deionized water to the desired protein concentration.
• Background Information
  Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   LILRB2  
• Gene symbol
  LILRB2
• Short name
  CellExp™ LILRB2, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ leukocyte immunoglobulin-like receptor, subfamily B (including TM and ITIM domains), member 2, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2, CD85D and ILT-4 and ILT4 and LIR-2 and LIR2 and MIR-10 and MIR10, LILRB2 and IDBG-68447 and ENSG00000131042 and 10288, cell adhesion molecule binding, Extracellular

Gene info

• Identity
  HGNC:6606
• Gene
  LILRB2
• Long gene name
  leukocyte immunoglobulin like receptor B2
• Synonyms gene name
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
• Synonyms
  • LIR-2
  • ILT4
  • MIR-10
  • LIR2
  • CD85d
  • MIR10
• Synonyms name
  • myeloid inhibitory receptor 10
  • leucocyte Ig-like receptor B2
• GenBank acession
  • AF000574
• Locus
  19q13.4
• Discovery year
  2000-01-11
• Pubmed identfication
  • 9151699
  • 9079806
• Classification
  • Ig-like cell adhesion molecule family
  • Inhibitory leukocyte immunoglobulin like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000064896

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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