Cystathionine β-Synthase Antibody

• Catalog number
  A1112-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  CBS
• Target Alternative Name
  Beta-thionase, Serine sulfhydrase, Cystathionine beta-synthase
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human CBS (Cat. No. 7844)
• Accession
  P35520
• Gene Id
  875
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  In PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin® and 50 % glycerol
• Purification
  Affinity purified rabbit IgG
• Application
  WB
• Positive Control
  WB: Hela cell lysates, rh-CBS
• Application And Usages
  WB: 1-4 µg
• Description
  Cystathionine β-synthase (CBS; E.C. 4.2.1.22) is a PLP-dependent enzyme which plays a central role in sulfur amino acid metabolism in eukaryotes. CBS catalyzes condensation between serine and homocysteine to generate cystathionine, which is then further processed by cystathionine γ-lyase to yield cysteine. The gene encoding CBS is essentially linked to the genetic disorders of homocystinuria and Down syndrome. Homocystinuria is an autosomal recessive disease, characterized by high plasma levels of homocysteine, with clinical manifestations including mental retardation, thromboembolism and connective tissue defects. In addition, CBS also mediates synthesis of hydrogen sulfide by catalyzing condensation between cysteine and homocysteine. CBS is highly expressed in the nervous system, liver and kidney and is responsible for up to 95% of the H2S production in the brain.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Cystathionine   β-Synthase  
• Gene symbol
  CBS
• Short name
  Cystathionine β-Synthase Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Cystathionine β-Synthase (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:1550
• Gene
  CBS
• Long gene name
  cystathionine beta-synthase
• Synonyms gene name
  • cystathionine-beta-synthase
• Synonyms
  • HIP4
• GenBank acession
  • L14577
• Locus
  21q22.3
• Discovery year
  2001-06-22
• Entrez gene record
  875
• Pubmed identfication
  • 9790750
• RefSeq identity
  • NM_000071
• VEGA ID
  OTTHUMG00000086834
• Locus Specific Databases
  • Cystathionine beta-synthase database
  • LRG_777

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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