AMG-900

• Catalog number
  B1343-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-[4-[3-(2-aminopyrimidin-4-yl)pyridin-2-yl]oxyphenyl]-4-(4-methylt hiophen-2-yl)phthalazin-1-amine
• Description
  AMG-900 is a highly sensitive and orally bioavailable inhibitor of Aurora Kinase with IC50 values of 5 nmol/L
• CAS Number
  945595-80-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C28H21N7OS
• Molecular Weight
  503.58
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO > 10 mM
• Handling
  Protect from air and light
• Tag Line
  A highly sensitive and orally bioavailable inhibitor of Aurora Kinase
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD18633194
• PubChem CID
  24856041
• PubChem CID Link
• SMILES
  CC1=CSC(=C1)C2=NN=C(C3=CC=CC=C32)NC4=CC=C(C=C4)OC5=C(C=CC=N5)C6=NC(=NC=C6)N
• InChi
  1S/C28H21N7OS/c1-17-15-24(37-16-17)25-20-5-2-3-6-21(20)26(35-34-25)32-18-8-10-19(11-9-18)36-27-22(7-4-13-30-27)23-12-14-31-28(29)33-23/h2-16H,1H3,(H,32,35)(H2,29,31,33)
• InChi Key
  IVUGFMLRJOCGAS-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  AMG-900  
• Gene symbol
  AMELX
• Short name
  AMG-900
• Alternative name
  AMG-900

Gene info

• Identity
  HGNC:461
• Gene
  AMELX
• Long gene name
  amelogenin X-linked
• Synonyms gene
  • AMG
  • AIH1
• Synonyms gene name
  • amelogenin (X chromosome, amelogenesis imperfecta 1)
• Synonyms name
  • amelogenesis imperfecta 1
• Locus
  Xp22.2
• Discovery year
  1988-05-11
• Entrez gene record
  265
• Pubmed identfication
  • 1734713
• RefSeq identity
  • NM_001142
• VEGA ID
  OTTHUMG00000021130
• Locus Specific Databases
  • Global Variome shared LOVD

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