Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one, Akti-1/2)

• Catalog number
  MBS6074625
• Price
  Please ask
• Size
  1 mg

• Other size
  please contact us to order other different size
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,

• Gene target
  Akt   Inhibitor   VIII   Isozyme-Selective   Akti-1/2   3-Dihydro-1   6-phenyl-1H-imidazo[4   5-g]quinoxalin-7-yl   phenyl   methyl   4-piperidinyl   2H-benzimidazol-2-one   Akti-1/2  
• Gene symbol
  COX8A, VSIR, MIR7-2, TRN-GTT2-7, G3BP1, TRI-AAT7-2, PIRC34, FAM3A
• Short name
  Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (1 3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4 5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one, Akti-1/2)
• Alternative name
  Akt suppressor VIII, Isozyme-Selective, Akti-1/2 (1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one, Akti-1/2)

Gene info

• Identity
  HGNC:2294
• Gene
  COX8A
• Long gene name
  cytochrome c oxidase subunit 8A
• Synonyms gene
  • COX8
• Synonyms gene name
  • cytochrome c oxidase subunit VIII
  • cytochrome c oxidase subunit VIIIA (ubiquitous)
• Synonyms
  • COX8-2
  • COX8L
  • VIII-L
  • COX
  • VIII
• GenBank acession
  • J04823
• Locus
  11q13.1
• Discovery year
  1989-06-30
• Entrez gene record
  1351
• Pubmed identfication
  • 2543673
  • 2847943
  • 26685157
• RefSeq identity
  • NM_004074
• Classification
  • Mitochondrial complex IV: cytochrome c oxidase subunits
• VEGA ID
  OTTHUMG00000167785

Gene info

• Identity
  HGNC:30085
• Gene
  VSIR
• Long gene name
  V-set immunoregulatory receptor
• Synonyms gene
  • C10orf54
• Synonyms gene name
  • chromosome 10 open reading frame 54
• Synonyms
  • SISP1
  • GI24
  • B7-H5
  • B7H5
  • VISTA
  • PD-1H
  • Dies1
• Synonyms name
  • stress induced secreted protein 1
  • V-domain Ig suppressor of T cell activation
  • PDCD1 homolog
• GenBank acession
  • AF193048
• Locus
  10q22.1
• Discovery year
  2005-10-06
• Entrez gene record
  64115
• Pubmed identfication
  • 12975309
  • 24691993
  • 25279955
• RefSeq identity
  • NM_022153
• Classification
  • B7 family
  • V-set domain containing
• VEGA ID
  OTTHUMG00000018426

Gene info

• Identity
  HGNC:31639
• Gene
  MIR7-2
• Long gene name
  microRNA 7-2
• Synonyms gene
  • MIRN7-2
• Synonyms
  • hsa-mir-7-2
• Locus
  15q26.1
• Discovery year
  2004-04-23
• Entrez gene record
  407044
• RefSeq identity
  • NR_029606
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:54714
• Gene
  TRN-GTT2-7
• Long gene name
  tRNA-Asn (anticodon GTT) 2-7
• Synonyms
  • tRNA-Asn-GTT-2-7
• Locus
  1q21.1
• Discovery year
  2019-12-06
• Entrez gene record
  7214
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:30292
• Gene
  G3BP1
• Long gene name
  G3BP stress granule assembly factor 1
• Synonyms gene name
  • GTPase activating protein (SH3 domain) binding protein 1
• Synonyms
  • HDH-VIII
  • G3BP
• Synonyms name
  • Ras-GTPase-activating protein SH3-domain-binding protein
  • DNA helicase VIII
• GenBank acession
  • BC006997
• Locus
  5q33.1
• Discovery year
  2006-10-25
• Entrez gene record
  10146
• Pubmed identfication
  • 8649363
  • 9889278
  • 25229650
• RefSeq identity
  • NM_005754
• Classification
  • RNA binding motif containing
  • Endoribonucleases
• VEGA ID
  OTTHUMG00000130123

Gene info

• Identity
  HGNC:34970
• Gene
  TRI-AAT7-2
• Long gene name
  tRNA-Ile (anticodon AAT) 7-2
• Synonyms gene
  • TRNAI25
• Synonyms gene name
  • transfer RNA isoleucine 25 (anticodon AAU)
  • transfer RNA-Ile (AAT) 7-2
• Synonyms
  • tRNA-Ile-AAT-7-2
• GenBank acession
  • HG983854
• Locus
  6p22.2
• Discovery year
  2008-08-29
• Entrez gene record
  107986683
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:37538
• Gene
  PIRC34
• Long gene name
  piwi-interacting RNA cluster 34
• Locus
  7
• Discovery year
  2009-11-05
• Entrez gene record
  100313890
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:13749
• Gene
  FAM3A
• Long gene name
  FAM3 metabolism regulating signaling molecule A
• Synonyms gene name
  • family with sequence similarity 3 member A
• Synonyms
  • DXS560S
  • 2-19
  • XAP-7
• GenBank acession
  • X74610
• Locus
  Xq28
• Discovery year
  2002-06-18
• Entrez gene record
  60343
• Pubmed identfication
  • 27688071
  • 26939760
  • 26492522
• VEGA ID
  OTTHUMG00000013418
• Locus Specific Databases
  • Global Variome shared LOVD

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