SQSTM1 Antibody, HRP Conjugated

• Catalog number
  bs-2951R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  SQSTM1 Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SQSTM1
• Specificity
  This is a highly specific antibody against SQSTM1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  80-130/440
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic peptide derived from human SQSTM1/Ubiquitin-binding protein p62
• Gene ID number
  8878
• Swiss Prot
  Q13501
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  p60; p62; A170; OSIL; PDB3; ZIP3; p62B; Sequestosome-1; EBI3-associated protein of 60 kDa; EBIAP; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin-binding protein p62; SQSTM1; ORCA
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  SQSTM1   Conjugated  
• Gene symbol
  SQSTM1
• Short name
  Anti-SQSTM1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-SQSTM1 PAb HRP
• Alternative technique
  antibodies
• Alternative to gene target
  sequestosome 1, A170 and OSIL and p60 and p62 and p62B and PDB3 and ZIP3, SQSTM1 and IDBG-61811 and ENSG00000161011 and 8878, K63-linked polyubiquitin binding, nuclei, Sqstm1 and IDBG-168358 and ENSMUSG00000015837 and 18412, BT.105440 and IDBG-640935 and ENSBTAG00000015591 and 338045

Gene info

• Identity
  HGNC:11280
• Gene
  SQSTM1
• Long gene name
  sequestosome 1
• Synonyms gene
  • PDB3
  • OSIL
• Synonyms gene name
  • Paget disease of bone 3
  • oxidative stress induced like
• Synonyms
  • p62
  • p60
  • p62B
  • A170
• Synonyms name
  • autophagy receptor p62
• GenBank acession
  • U46751
• Locus
  5q35.3
• Discovery year
  2000-06-13
• Entrez gene record
  8878
• Pubmed identfication
  • 8650207
  • 8551575
• Classification
  • Zinc fingers ZZ-type
• VEGA ID
  OTTHUMG00000150643

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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