TM-5275 Sodium salt

• Catalog number
  B1884-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  5-Chloro-2-[[2-[2-[4-(Diphenylmethyl)-1-piperazinyl]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt
• Description
  TM-5275 sodium salt is an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor. TM 5275 prolongs tPA retention and enhances plasmin generation on the vascular endothelial cell (VEC) surface as a result of PAI-1 inhibition.
• CAS Number
  1103926-82-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₈H₂₇ClN₃NaO₅
• Molecular Weight
  543.98
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and moisture
• Tag Line
  An orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD28396414
• PubChem CID
  53240409
• PubChem CID Link
• SMILES
  C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)COCC(=O)NC4=C(C=C(C=C4)Cl)C(=O)[O-].[Na+]
• InChi
  InChI=1S/C28H28ClN3O5.Na/c29-22-11-12-24(23(17-22)28(35)36)30-25(33)18-37-19-26(34)31-13-15-32(16-14-31)27(20-7-3-1-4-8-20)21-9-5-2-6-10-21;/h1-12,17,27H,13-16,18-19H2,(H,30,33)(H,35,36);/q;+1/p-1
• InChi Key
  JSHSGBIWNPQCQZ-UHFFFAOYSA-M
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  TM-5275   Sodium   salt  
• Gene symbol
  MT-TM, TSPAN16, ACP3, P4HTM
• Short name
  TM-5275 Sodium salt
• Alternative name
  TM-5275 Sodium salt

Gene info

• Identity
  HGNC:7492
• Gene
  MT-TM
• Long gene name
  mitochondrially encoded tRNA-Met (AUA/G)
• Synonyms gene
  • MTTM
• Synonyms gene name
  • tRNA methionine
  • mitochondrially encoded tRNA methionine
• Synonyms
  • trnM
• Locus
  mitochondria
• Discovery year
  1989-10-12
• Entrez gene record
  4569
• Pubmed identfication
  • 7219534
• Classification
  • Mitochondrially encoded transfer RNAs

Gene info

• Identity
  HGNC:30725
• Gene
  TSPAN16
• Long gene name
  tetraspanin 16
• Synonyms gene
  • TM4SF16
• Synonyms gene name
  • transmembrane 4 superfamily member 16
• Synonyms
  • TM4-B
  • TM-8
• GenBank acession
  • BC029908
• Locus
  19p13.2
• Discovery year
  2004-10-19
• Entrez gene record
  26526
• Pubmed identfication
  • 10500248
• RefSeq identity
  • NM_012466
• Classification
  • Tetraspanins
• VEGA ID
  OTTHUMG00000180833

Gene info

• Identity
  HGNC:125
• Gene
  ACP3
• Long gene name
  acid phosphatase 3
• Synonyms gene
  • ACPP
• Synonyms gene name
  • acid phosphatase, prostate
• Synonyms
  • ACP-3
  • PAP
  • TM-PAP
• Synonyms name
  • prostatic acid phosphatase
• Locus
  3q22.1
• Discovery year
  1989-05-30
• Entrez gene record
  55
• Pubmed identfication
  • 1375464
  • 2842184
• RefSeq identity
  • NM_001099
• Classification
  • Acid phosphatases
• VEGA ID
  OTTHUMG00000159650

Gene info

• Identity
  HGNC:28858
• Gene
  P4HTM
• Long gene name
  prolyl 4-hydroxylase, transmembrane
• Synonyms gene name
  • prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
• Synonyms
  • P4H-TM
  • PHD4
  • PH4
  • HIFPH4
  • FLJ20262
  • EGLN4
  • PH-4
• Synonyms name
  • Prolyl hydroxlase domain-containing 4
  • hypoxia inducible factor prolyl 4 hydroxylase
• Locus
  3p21.31
• Discovery year
  2008-12-08
• Entrez gene record
  54681
• Pubmed identfication
  • 12163023
  • 17726031
• RefSeq identity
  • NM_177938
• VEGA ID
  OTTHUMG00000074057

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