This antibody has been succesfully tested for use in following methods:
Target of this antibody:
Formulation of this antibody:
In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
Alternative names of antibody target:
Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD144
WB; 1:500 – 1:2000
Shelf time: 12 months in temp.: -20 deg.C
This antibody reacts with:
Clonality of antibody:
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD144
How to handle this antibody:
The antibody solution should be gently mixed before use
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
Form of antibody:
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
anti-CD144 (VE-Cadherin) Antibody
antibody to-CD144 (VE-Cadherin) (Antibody to)