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Also known as
ErbB4
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Other names
erbB4; EGF-like growth factor receptor ErbB4 extracellular domain; receptor tyrosine-protein kinase erbB-4; OTTMUSP00000030425; OTTMUSP00000030426; OTTMUSP00000030427; avian erythroblastosis oncogene B 4; proto-oncogene-like protein c-ErbB-4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
Erbb4; Erbb4; Her4; c-erbB-4; N/A
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Gene name synonims
Erbb4; Erbb4; Her4; c-erbB-4; N/A
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Other gene names
Erbb4; Erbb4; Her4; c-erbB-4; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
N/A
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Clone
10J101
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Host organism
Rabbit (Oryctolagus cuniculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes human ErbB4 at ~180kD only when phosphorylated at Tyrosine 1284. Species Crossreactivity: mouse, rat; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Supernatant
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Form Appearance
Supplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applications
Western Blot (WB), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Description
For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translation
anticorps
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Gene target
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Gene symbol
ERBB4
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Short name
ErbB4, phosphorylated (Y1284) (Receptor Tyrosine-protein Kinase erbB-4, Proto-oncogene-like Protein c-ErbB-4, p180erbB4, Tyrosine Kinase- Surface Receptor HER4, ERBB4) Antibody
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Technique
Antibody, antibodies against human proteins, antibodies for
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Alternative name
Anti-ErbB4, phosphorylated (Y1284) (Receptor Tyrosine-protein Kinase erbB-4, Proto-oncogene-like Protein c-ErbB-4, p180erbB4, Tyrosine Kinase-type Cell Surface Receptor HER4, ERBB4)
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Alternative technique
antibodies
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Alternative to gene target
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian), ALS19 and HER4 and p180erbB4, ERBB4 and IDBG-79992 and ENSG00000178568 and 2066, transferase activity, nuclei, Erbb4 and IDBG-164078 and ENSMUSG00000062209 and 13869, ERBB4 and IDBG-643612 and ENSBTAG00000012647 and
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Tissue
cell
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