CUDC-305

  • Catalog number
    9653-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    2-((6-(dimethylamino)benzo[d][1,3]dioxol-5-yl)thio)-1-(2-(neopentylamino)ethyl)-1H-imidazo[4,5-c]pyridin-4-amine; Debio-0932
  • Description
    CUDC-305 is a potent inhibitor of Heat Shock Proteins, displaying high affinity for HSP90α/β (IC₅₀ = 100 nM) and HSP90 complex derived from cancer cells (IC₅₀ = 48.8 nM).
  • CAS Number
    1061318-81-7
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₂H₃₀N₆O₂S
  • Molecular Weight
    442.58
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>10 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A potent inhibitor of Heat Shock Proteins, displaying high affinity for HSP90α/β
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    44156921
  • SMILES
    CC(C)(C)CNCCN1C2=C(C(=NC=C2)N)N=C1SC3=CC4=C(C=C3N(C)C)OCO4
  • InChi
    InChI=1S/C22H30N6O2S/c1-22(2,3)12-24-8-9-28-14-6-7-25-20(23)19(14)26-21(28)31-18-11-17-16(29-13-30-17)10-15(18)27(4)5/h6-7,10-11,24H,8-9,12-13H2,1-5H3,(H2,23,25)
  • InChi Key
    RVJIQAYFTOPTKK-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    CUDC-305
  • Alternative name
    CUDC-305
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