CBHA
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Catalog number2284-5
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PricePlease ask
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Size5 mg
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Alternative_nameN-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-benzamide; m-Carboxycinnamic Acid bis-Hydroxamide
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DescriptionA potent histone deacetylase (HDAC) inhibitor (ID₅₀ values of 0.01 and 0.07 μM in vitro for HDAC1 and HDAC3, respectively). CBHA also induces apoptosis in nine different neuroblastoma cell lines in culture (0.5-4.0 μM) and completely suppresses neuroblastoma tumor growth in SCID mice at 200 mg/ kg.
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CAS Number174664-65-4
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Structure AvailableYes
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Peptide sequenceNo
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Salt FormNo
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Molecular FormulaC₁₀H₁₀N₂O₄
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Molecular Weight222.2
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Cell PermeableYes
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Purity≥98%
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SolubilitiesDMSO
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HandlingProtect from light and moisture
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Tag LineA potent HDAC1 and HDAC3 inhibitor
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Storage Condition-20 ̊C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD03453553
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PubChem CID5353484
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SMILESC1=CC(=CC(=C1)C(=O)NO)C=CC(=O)NO
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InChiInChI=1S/C10H10N2O4/c13-9(11-15)5-4-7-2-1-3-8(6-7)10(14)12-16/h1-6,15-16H,(H,11,13)(H,12,14)/b5-4+
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InChi KeyOYKBQNOPCSXWBL-SNAWJCMRSA-N
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MSDS AvailableYes
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Gene target
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Short nameCBHA
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Alternative nameCBHA
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