Terazosin Hydrochloride, Alpha adrenergic antagonist, and Hsp90 Activator

• Catalog number
  SIH-516-100MG
• Price
  Please ask
• Size
  100 mg

• Stock availabilitIn Stock
  In Stock
• CAS number
  63074-08-8
• Description
  Alpha adrenergic antagonist, and Hsp90 Activator
• Molecular weight
  423,89 g/mol
• Primary research fields
  Cancer, Apoptosis, Neuroscience, Neurotransmitter Receptors, Alpha-2 Adrenergic Receptors
• Other name
  1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine
• Product category
  Small Molecules
• Product type
  Antagonist
• Chemical formula
  C19H25N5O4·HCl
• Origin
  Synthetic
• Purity pourcentage
  >98%
• Soluble in
  Soluble to 20mg/ml in warm water
• Physical appearance
  White to off-white solid
• Storage recommendations
  -20ºC
• Shipping recommendations
  Shipped Ambient
• Safety information
  Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard Statements: H302 - Harmful if swallowed.
• PubChem number
  44383
• Scientific context
  Terazosin (TZ) which is marketed as an alpha1-adrenergic receptor antagonist, has been shown to alleviate organ damaged and increase survival in rodent models of sepsis and stroke in vivo (1). It inhibits apoptosis in macrophages by activation of Pgk1 and Hsp90 (1).
• Bibliography
  1. Chen X., et al. (2015) Nature Chem Biol. 11:19-25. 2. Hancock A.A., et al. (1995) J Recept Signal Transduct Res. 15: 863. 3. Kyncl J.J. (1986) Am J Med. 80:12.
• Release date
  11-Aug-2015
• PubMed number
  Refer to PubMed
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• Representative figure link
• Representative figure legend
  Chemical structure of Terazosin Hydrochloride (SIH-516), a Alpha adrenergic antagonist, and Hsp90 Activator. CAS #: 63074-08-8. Molecular Formula: C19H25N5O4 · HCl. Molecular Weight: 423.89 g/mol. Chemical structure of Terazosin Hydrochloride, a Alpha adrenergic antagonist, and Hsp90 Activator (SIH-516). CAS # 63074-08-8. Molecular Formula: C19H25N5O4 · HCl.
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  0.25
• Net weight g
  0.1
• Other related products
• Additional description
  The Terazosin Hydrochloride, Alpha adrenergic antagonist, Hsp90 Activator is a α- or alpha protein sometimes glycoprotein present in blood. The antagonist receptor ligand binding will be in contrast with agonist activity. stressma produces more antagonist and receptor related products as 1.

• Gene target
  Terazosin   Hydrochloride   Alpha   adrenergic   antagonist   Hsp90   Activator  
• Short name
  Terazosin Hydrochloride, Alpha adrenergic antagonist, Hsp90 Activator
• Alternative name
  Terazosin Hydrochloride, a adrenergic antagonist, and Hsp90 Activator

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