GW501516

• Catalog number
  1971-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  (2-Methyl-4-(((4-methyl-2-(4-trifluoromethylphenyl)-1,3-thiazol-5-yl)methyl)sulfanyl)phenoxy)acetic acid
• Description
  A selective agonist for PPARδ (peroxisome proliferator-activated receptorδ) (EC₅₀ = 1. 1 nM), displaying 1000-fold selectivity over the other human subtypes. In macrophages, fibroblasts, and intestinal cells, GW501516 increases expression of the reverse cholesterol transporter ATP-binding cassette A1 and induces apolipoprotein A1-specific cholesterol efflux.
• CAS Number
  317318-70-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₁₈F₃NO₃S₂
• Molecular Weight
  453.5
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (50 mg/ml) or EtOH (12 mg/ml)
• Handling
  Protect from light and air
• Tag Line
  A selective agonist for PPARδ
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  48 months
• MDL Number
  MFCD09033000
• PubChem CID
  9803963
• PubChem CID Link
• SMILES
  CC1=C(C=CC(=C1)SCC2=C(N=C(S2)C3=CC=C(C=C3)C(F)(F)F)C)OCC(=O)O
• InChi
  InChI=1S/C21H18F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13 (2)25-20(30-18)14-3-5-15(6-4-14)21(22,23)24/h3-9H,10-11H2,1-2H3,(H,26, 27)
• InChi Key
  YDBLKRPLXZNVNB-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  GW501516  
• Short name
  GW501516
• Alternative name
  GW501516

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