PI-3065

• Catalog number
  B1674-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  PI-3065; PI3065; PI 3065; 4-(6-((4-(cyclopropylmethyl)piperazin-1-yl)methyl)-2-(5-fluoro-1H-indol-4-yl)thieno[3,2-d]pyrimidin-4-yl)morpholine
• Description
  PI-3065 is a small molecule and selective inhibitor of p110δkinase with an Ki value of 1.5nM and IC50 value of 5nM.
• CAS Number
  955977-50-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₇H₃₁FN₆OS
• Molecular Weight
  506.64
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A P110δkinase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  24937012
• PubChem CID Link
• SMILES
  C1CC1CN2CCN(CC2)CC3=CC4=C(S3)C(=NC(=N4)C5=C(C=CC6=C5C=CN6)F)N7CCOCC7
• InChi
  InChI=1S/C27H31FN6OS/c28-21-3-4-22-20(5-6-29-22)24(21)26-30-23-15-19(17-33-9-7-32(8-10-33)16-18-1-2-18)36-25(23)27(31-26)34-11-13-35-14-12-34/h3-6,15,18,29H,1-2,7-14,16-17H2
• InChi Key
  YDNOHCOYQVZOMC-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  PI-3065  
• Gene symbol
  MIR3065, SERPINF2, PDIA3, SERPINA1
• Short name
  PI-3065
• Alternative name
  PI-3065

Gene info

• Identity
  HGNC:38234
• Gene
  MIR3065
• Long gene name
  microRNA 3065
• Synonyms
  • hsa-mir-3065
• Locus
  17q25.3
• Discovery year
  2010-04-30
• Entrez gene record
  100422915
• RefSeq identity
  • NR_036151
• Classification
  • MicroRNAs

Gene info

• Identity
  HGNC:9075
• Gene
  SERPINF2
• Long gene name
  serpin family F member 2
• Synonyms gene
  • PLI
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
• Synonyms
  • API
  • ALPHA-2-PI
  • A2AP
  • AAP
  • alpha2AP
• Synonyms name
  • alpha-2-plasmin inhibitor
  • alpha-2-antiplasmin
• GenBank acession
  • D00174
• Locus
  17p13.3
• Discovery year
  1989-04-14
• Entrez gene record
  5345
• Pubmed identfication
  • 3416655
  • 24172014
• RefSeq identity
  • NM_000934
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000090552
• Locus Specific Databases
  • LRG_885

Gene info

• Identity
  HGNC:4606
• Gene
  PDIA3
• Long gene name
  protein disulfide isomerase family A member 3
• Synonyms gene
  • GRP58
• Synonyms gene name
  • glucose regulated protein, 58kDa
  • protein disulfide isomerase-associated 3
  • protein disulfide isomerase family A, member 3
• Synonyms
  • P58
  • ERp61
  • ERp57
  • ERp60
  • GRP57
  • PI-PLC
  • HsT17083
• Locus
  15q15.3
• Discovery year
  1997-06-09
• Entrez gene record
  2923
• Pubmed identfication
  • 8974399
• RefSeq identity
  • NM_005313
• Classification
  • Protein disulfide isomerases
• VEGA ID
  OTTHUMG00000044444

Gene info

• Identity
  HGNC:8941
• Gene
  SERPINA1
• Long gene name
  serpin family A member 1
• Synonyms gene
  • PI
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
• Synonyms
  • AAT
  • A1A
  • PI1
  • alpha-1-antitrypsin
  • A1AT
  • alpha1AT
• Synonyms name
  • protease inhibitor 1
  • anti-elastase
  • alpha-1 antitrypsin
  • alpha-1 proteinase inhibitor
• GenBank acession
  • X01683
• Locus
  14q32.13
• Discovery year
  1986-01-01
• Entrez gene record
  5265
• Pubmed identfication
  • 24172014
• RefSeq identity
  • NM_001002235
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000150355
• Locus Specific Databases
  • LRG_575

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