Sulfo-NHS

Alternative_name

Hydroxy-2,3-dixopyrrolidine-3-sulfonic acid sodium salt; Sulfo-NHS; SNHS; N-Hydroxysulfosuccinimide sodium salt
Description

KEY FEATURES: • Sulfo-NHS assists in stabilizing the protein-EDC intermediate, thus allowing for a more efficient crosslinking reaction. • Water-soluble; can be used under physiologic conditions • Assists in converting carboxyl groups to sulfo-NHS esters which react with primary amines APPLICATIONS: • Increases the efficiency of EDC-mediated coupling reactions • Useful for covalently binding proteins or peptides to carboxyl containing beads, resins, or other nanoparticles • Assists in converting carboxyl groups to primary amine-reactive sulfo-NHS esters
CAS Number

106627-54-7
Structure Available

Yes
Salt Form

No
Molecular Formula

C₄H₄NNaO₆S
Molecular Weight

217.13
Cell Permeable

No
Purity

≥95% by NMR
Solubilities

H₂O (~ 2 mg/ml)
Handling

Protect from moisture
Tag Line

A useful catalyst in the zero-length crosslinking of proteins
Storage Condition

+4 ̊C
Shipping Condition

Gel Pack
Shelf Life

36 months
MDL Number

MFCD00043100
PubChem CID

3520574
PubChem CID Link
SMILES

C1C(C(=O)N(C1=O)O)S(=O)(=O)[O-].[Na+]
InChi

InChI=1S/C4H5NO6S.Na/c6-3-1-2(12(9,10)11)4(7)5(3)8;/h2,8H,1H2,(H,9,10,11);/q;+1/p-1
InChi Key

RPENMORRBUTCPR-UHFFFAOYSA-M
Data Sheet Link
MSDS Available

Yes

Identity

HGNC:7820
Gene

NHS
Long gene name

NHS actin remodeling regulator
Synonyms gene name
- Nance-Horan syndrome (congenital cataracts and dental anomalies)
Locus

Xp22.2-p22.13
Discovery year

1989-06-30
Entrez gene record

4810
Pubmed identfication
- 20332100
RefSeq identity
- NM_198270
Classification
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000022799
Locus Specific Databases
- Global Variome shared LOVD