LLGL1 + LLGL2(Ser650+Ser654) Antibody, ALEXA FLUOR 488

• Catalog number
  bs-6070R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  LLGL1 + LLGL2(Ser650+Ser654) Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-LLGL1 + LLGL2 Ser650+Ser654 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  LLGL1 + LLGL2 Ser650+Ser654
• Specificity
  This is a highly specific antibody against LLGL1 + LLGL2 Ser650+Ser654.
• Modification
  Phosphorylation
• Modification Site
  Ser650+Ser654
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654
• Gene ID Number
  3996
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  LLGL1 + LLGL2 phospho S650 + S654; LLGL1 + LLGL2 phospho Ser650 + Ser654; p-LLGL1 + p-LLGL2 S650 + S654; p-LLGL1/LLGL2 Ser650 + Ser654; p-LLGL1/LLGL2 S650 + S654; p-LLGL1/LLGL2 Ser650/654; DLG4; HGL; HUGL; HUGL1; lethal giant larvae homolog 1; lethal giant larvae homolog 2; Lethal2 giant larvae protein homolog 1; Lethal2 giant larvae protein homolog 2; LGL2; LLGL; L2GL1_HUMAN; L2GL2_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-LLGL1 + LLGL2 Ser650+Ser654 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  LLGL1   LLGL2   Ser650+Ser654  
• Gene symbol
  LLGL2, LLGL1
• Short name
  Anti-LLGL1 + LLGL2 Ser650+Ser654
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  LLGL1 + LLGL2(Ser650+Ser654) Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  lethal giant larvae homolog 1 (Drosophila), DLG4 and HUGL and HUGL-1 and HUGL1 and LLGL, LLGL1 and IDBG-33645 and ENSG00000131899 and 3996, protein kinase binding, Cytoplasm, Llgl1 and IDBG-181336 and ENSMUSG00000020536 and 16897, LLGL1 and IDBG-638036 and ENSBTAG00000004635 and 781865

Gene info

• Identity
  HGNC:6629
• Gene
  LLGL2
• Long gene name
  LLGL scribble cell polarity complex component 2
• Synonyms gene name
  • lethal giant larvae homolog 2 (Drosophila)
  • lethal giant larvae homolog 2, scribble cell polarity complex component
  • LLGL2, scribble cell polarity complex component
• Synonyms
  • HGL
  • Hugl-2
• GenBank acession
  • X87342
• Locus
  17q25.1
• Discovery year
  1997-01-28
• Entrez gene record
  3993
• Pubmed identfication
  • 22580609
• RefSeq identity
  • NM_004524
• Classification
  • WD repeat domain containing
  • Scribble complex
• VEGA ID
  OTTHUMG00000179685

Gene info

• Identity
  HGNC:6628
• Gene
  LLGL1
• Long gene name
  LLGL scribble cell polarity complex component 1
• Synonyms gene
  • DLG4
  • LLGL
  • HUGL
  • HUGL-1
• Synonyms gene name
  • lethal giant larvae homolog 1 (Drosophila)
  • lethal giant larvae homolog 1, scribble cell polarity complex component
• Synonyms
  • Lgl1
  • Mgl1
• Locus
  17p11.2
• Discovery year
  1995-09-12
• Entrez gene record
  3996
• Pubmed identfication
  • 7542763
  • 8565641
• Classification
  • Scribble complex
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000059396

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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