anti-USP7 Antibody

• Catalog number
  49-498
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  HAUSP (also known as deubiquitinating enzyme 7, herpes virus associated ubiquitin specific protease, TEF1, ubiquitin carboxyl terminal hydrolase 7, ubiquitin specific protease 7, ubiquitin thiolesterase 7, and USP7) is a novel p53 interacting protein. HAUSP was identified by mass spectrometry of affinity-purified p53 associated factors by Li et al. HAUSP strongly stabilizes p53 even in the presence of excess MDM2, and also induces p53-dependent cell growth repression and apoptosis. HAUSP has an intrinsic enzymatic activity that specifically de-ubiquitinates p53 both in vivo and in vitro. Expression of a catalytically inactive point mutation of HAUSP in cells increased the levels of p53 ubiquitination and also destabilized p53. Li et al concluded that their findings revealed an important mechanism by which p53 can be stabilized by direct de-ubiquitination and also implied that HAUSP may function as a tumor suppressor in vivo through the stabilization of p53.
• Gene names
  USP7, Deubiquitinating enzyme 7, HAUSP, TEF1, Ubiquitin specific protease 7, Ubiquitin thioesterase 7
• Antibodie s label
  unlabelled serum
• Purity
  Immunoaffinity Chromatography
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  USP7 antibody was made against amino acids 169 - 180 of USP7 (Human).
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  USP7 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 ug/mL.
• Suspention pH azide
  0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
• Keep at
  Store USP7 antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Human
• Omim nr
  212276477
• Ncbi nr
  Q93009
• Vial with antibody
  in solution
• NCBI GENE nr
  7874
• GENE symbol
  USP7
• Antigene name
  ubiquitin specific peptidase 7 (herpes virus-associated)
• Source
  Homo sapiens
• Protein nr
  Q93009
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  USP7  
• Gene symbol
  USP7, USP7-AS1
• Short name
  anti-USP7 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toUSP7 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12630
• Gene
  USP7
• Long gene name
  ubiquitin specific peptidase 7
• Synonyms gene
  • HAUSP
• Synonyms gene name
  • ubiquitin specific peptidase 7 (herpes virus-associated)
• GenBank acession
  • Z72499
• Locus
  16p13.2
• Discovery year
  1998-10-12
• Entrez gene record
  7874
• Pubmed identfication
  • 12838346
  • 9925944
• Classification
  • Ubiquitin specific peptidases
• VEGA ID
  OTTHUMG00000176903

Gene info

• Identity
  HGNC:55379
• Gene
  USP7-AS1
• Long gene name
  USP7 antisense RNA 1
• Locus
  16p13.2
• Discovery year
  2020-11-12
• Entrez gene record
  105371074
• Classification
  • Antisense RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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