SEMA3E/Semaphorin 3E Antibody, ALEXA FLUOR 488

• Catalog number
  bs-11480R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  SEMA3E/Semaphorin 3E Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-SEMA3E/Semaphorin 3E PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SEMA3E/Semaphorin 3E
• Specificity
  This is a highly specific antibody against SEMA3E/Semaphorin 3E.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SEMA3E/Semaphorin 3E
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin†domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA3E is a secreted semaphorin with 775 amino acids. Mutations in the SEMA3E gene are associated with CHARGE syndrome, a disorder characterized by cranial nerve dysfunction, coloboma of the eye, choanal atresia, inner and external ear abnormalities, cardiac anomalies, genitourinary abnormalities, and growth retardation.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  Coll 5; Coll5; KIAA0331; M sema H; M SEMAH; M SemaK; Msema H; MSEMAH; MSemaK; SEM3E_HUMAN; Sema domain immunoglobulin domain Ig; Sema domain immunoglobulin domain Ig short basic domain secreted 3E; Sema domain, immunoglobulin domain Ig, short basic domain, secreted, semaphorin 3E; SEMA3E; SEMAH; Semaphorin 3E; Semaphorin-3E; Semaphorin3E; Short basic domain secreted semaphorin 3E; SEM3E_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-SEMA3E/Semaphorin 3E has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  SEMA3E/Semaphorin  
• Gene symbol
  SEMA3E
• Short name
  Anti-SEMA3E/Semaphorin 3E
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  SEMA3E/Semaphorin 3E Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E, coll-5 and M-SEMAH and M-SemaK and SEMAH, SEMA3E and IDBG-24532 and ENSG00000170381 and 9723, semaphorin receptor binding, Extracellular, Sema3e and IDBG-135740 and ENSMUSG00000063531 and 20349, SEMA3E and IDBG-631012 and ENSBTAG00000014920 and 535644

Gene info

• Identity
  HGNC:10727
• Gene
  SEMA3E
• Long gene name
  semaphorin 3E
• Synonyms gene
  • SEMAH
• Synonyms gene name
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
• Synonyms
  • M-SemaK
  • KIAA0331
  • coll-5
• Synonyms name
  • M-sema H
• GenBank acession
  • AB002329
• Locus
  7q21.11
• Discovery year
  1999-06-25
• Entrez gene record
  9723
• Pubmed identfication
  • 9205841
  • 9515811
• RefSeq identity
  • NM_012431
• Classification
  • Immunoglobulin like domain containing
  • Semaphorins
• VEGA ID
  OTTHUMG00000154693
• Locus Specific Databases
  • LRG_1287

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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