BIBF1120
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Catalog number2167-25
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PricePlease ask
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Size25 mg
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Alternative_name(Z)-methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1- yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6- carboxylate
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DescriptionBIBF1120 is a triple angiokinase inhibitor. It blocks signaling through vascular endothelial growth factor receptors (VEGFR; IC₅₀ values of 13 to 34 nM), platelet-derived growth factor receptors (PDGFR; IC₅₀ values of 59 to 65 nM), and fibroblast growth factor receptors (FGFR; IC₅₀ values of 37 to 610 nM).
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CAS Number928326-83-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₃₁H₃₃N₅O₄
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Molecular Weight539.62
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Cell PermeableYes
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Purity≥95%
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SolubilitiesDMSO (~ 6 mg/ml) or EtOH (~ 3 mg/ml)
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HandlingProtect from air and light
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Tag LineA triple angiokinase inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24months
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MDL NumberMFCD11974012
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PubChem CID9809715
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SMILESCN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)NC(=C3C4=C(C=C(C=C4)C(=O)OC)NC3=O)C5=CC=CC=C5
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InChiInChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-
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InChi KeyXZXHXSATPCNXJR-ZIADKAODSA-N
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MSDS AvailableYes
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Gene target
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Short nameBIBF1120
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Alternative nameBIBF1120
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