BIBF1120

  • Catalog number
    2167-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    (Z)-​methyl 3-​(((4-​(N-​methyl-​2-​(4-​methylpiperazin-​1-​ yl)acetamido)phenyl)amino)(phenyl)methylene)-​2-​oxoindoline-​6-​ carboxylate
  • Description
    BIBF1120 is a triple angiokinase inhibitor. It blocks signaling through vascular endothelial growth factor receptors (VEGFR; IC₅₀ values of 13 to 34 nM), platelet-derived growth factor receptors (PDGFR; IC₅₀ values of 59 to 65 nM), and fibroblast growth factor receptors (FGFR; IC₅₀ values of 37 to 610 nM).
  • CAS Number
    928326-83-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₃₁H₃₃N₅O₄
  • Molecular Weight
    539.62
  • Cell Permeable
    Yes
  • Purity
    ≥95%
  • Solubilities
    DMSO (~ 6 mg/ml) or EtOH (~ 3 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A triple angiokinase inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24months
  • MDL Number
    MFCD11974012
  • PubChem CID
    9809715
  • SMILES
    CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)NC(=C3C4=C(C=C(C=C4)C(=O)OC)NC3=O)C5=CC=CC=C5
  • InChi
    InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-
  • InChi Key
    XZXHXSATPCNXJR-ZIADKAODSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    BIBF1120
  • Alternative name
    BIBF1120
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