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Betacellulin Murine Recombinant

Betacellulin Murine Recombinant is available 2 times from Biovision labs

7119-10 | Betacellulin, Murine Recombinant size: 10 ug | 206.20 USD

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7119-50 | Betacellulin, Murine Recombinant size: 50 ug | 690.59 USD

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Synonyms BTC
Alternative_names BTC
Description A potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells
Recombinant Yes
Source E. coli.
Purity by SDS-PAGE ≥98%
Assay SDS-PAGE
Endotoxin Level< 0.1 ng/ug of protein (
Activity (Specifications/test method) Determined by its ability to stimulate the proliferation of mouse Balb/3T3 cells. The expected ED50 is ≤ 0.01 ng/ml, corresponding to a specific activity of ≥ 1 x 108 units/mg.
Biological activity Determined by its ability to stimulate the proliferation of mouse Balb/3T3 cells. The expected ED50 is ≤ 0.01 ng/ml, corresponding to a specific activity of ≥ 1 x 108 units/mg.
Molecular Weight 9 kDa
Storage Temp. -20°C
Shipping Gel Pack
Shelf Life 12 months
Appearance Lyophilized powder
Physical form description Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Background Information Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant murine Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein precursor.
Amino acid sequence DGNTTRTPET NGSLCGAPGE NCTGTTPRQK VKTHFSRCPK QYKHYCIHGR CRFVVDEQTP SCICEKGYFG ARCERVDLFY
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetBetacellulin Murine
Short name Betacellulin, Murine Recombinant
Technique Recombinant
Alternative name Betacellulin, Murine recombinant
Alternative technique rec
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