Macrophage Colony Stimulating Factor Receptor (M-CSFR, CSF-1) (PerCP)

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Description

Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Conjugate

Peridinin chlorophyll (PerCP)

Gene target

Macrophage Colony Stimulating Factor Receptor M-CSFR CSF-1
Gene symbol

CSF1, CPT1B, CSF2, IRAK3, PGAM2, CYP20A1, USP16, CYB5B, H3C14, CSF3
Short name

Macrophage Colony Stimulating Factor Receptor (M-CSFR, CSF-1) (PerCP)
Technique

Percp, Peridinin chlorophyll protein (PerCP) has a 677 nanometer maximum emission, red, when excited at 488 nanometers and the Macrophage Colony Stimulating Factor Receptor (M-CSFR, CSF-1) (PerCP) is detected on the FL3 detector of a FACSCalibur or FACScan. A PerCP dye is also available (PerCP-Cy5.5, also written Cy5.5-PerCP). PerCP is not suited for the high-powered lasing (>150mW) applications, such as on a MoFlo, due to it photobleaching (features/ qualities/ traits). PerCP conjugates can only be received/be gotten from the Becton Dickinson/Pharmingen group of companies or from MyBioSource.
Label

PerCP
Alternative name

Macrophage Colony Stimulating Factor Receptor (M-CSFR, CSF-1) (PerCP)
Alternative technique

antibodies-percp

Identity

HGNC:20503
Gene

H3C14
Long gene name

H3 clustered histone 14
Synonyms gene
- H3F2
- H3FM
- HIST2H3C
Synonyms gene name
- H3 histone family, member M
- histone 2, H3c
- histone cluster 2, H3c
- histone cluster 2 H3 family member c
Synonyms
- MGC9629
- H3/m
- H3
- H3.2
- H3/M
GenBank acession
- AF531307
Locus

1q21.2
Discovery year

2003-02-19
Entrez gene record

126961
Pubmed identfication
- 12408966
- 3013246
RefSeq identity
- NM_021059
Classification
- H3 histones
VEGA ID

OTTHUMG00000012190

Identity

HGNC:2438
Gene

CSF3
Long gene name

colony stimulating factor 3
Synonyms gene
- GCSF
- G-CSF
- C17orf33
Synonyms gene name
- chromosome 17 open reading frame 33
- colony stimulating factor 3 (granulocyte)
Synonyms
- MGC45931
Synonyms name
Locus

17q21.1
Discovery year

2001-06-22
Entrez gene record

1440
Pubmed identfication
- 3499671
- 3501046
RefSeq identity
- NM_172220
Classification
- Receptor ligands
VEGA ID

OTTHUMG00000133247

Name

Colony-Forming Units Assay
Concept

Scope note: A cytologic technique for measuring the functional capacity of stem cells by assaying their activity.
Tree numbers
- E01.370.225.500.383
- E05.200.500.383
- E05.242.383
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data