Motolimod

• Catalog number
  B1594-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  3H-1-Benzazepine-4-carboxamide, 2-amino-N,N-dipropyl-8-[4-(1-pyrrolidinylcarbonyl)phenyl; VTX-2337
• Description
  Motolimod (VTX-2337) is a potent and selective, small molecule Toll-like receptor (TLR) 8 agonist (EC₅₀ = 100 nM) that stimulates natural killer (NK) cells, dendritic cells, and monocytes. Useful in immunotherapy for multiple oncology indications, including squamous cell carcinoma of the head and neck (SCCHN).
• CAS Number
  926927-61-9
• Structure Available
  Yes
• Molecular Formula
  C₂₈H₃₄N₄O₂
• Molecular Weight
  458.6
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and selective, small molecule Toll-like receptor (TLR) 8 agonist
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  16049404
• PubChem CID Link
• SMILES
  CCCN(CCC)C(=O)C1=CC2=C(C=C(C=C2)C3=CC=C(C=C3)C(=O)N4CCCC4)N=C(C1)N
• InChi
  InChI=1S/C28H34N4O2/c1-3-13-31(14-4-2)28(34)24-17-23-12-11-22(18-25(23)30-26(29)19-24)20-7-9-21(10-8-20)27(33)32-15-5-6-16-32/h7-12,17-18H,3-6,13-16,19H2,1-2H3,(H2,29,30)
• InChi Key
  QSPOQCXMGPDIHI-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Motolimod  
• Short name
  Motolimod
• Alternative name
  Motolimod

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