AZD-8931

• Catalog number
  9659-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-[[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy]quinazoline; Sapitinib; Momelotinib.
• Description
  AZD-8931 is a potent, ATP competitive and reversible inhibitor of EGFR (ErbB-1), Neu (ErbB-2) and ErbB-3 (the IC₅₀ values are 4 nM, 3 nM and 4 nM, respectively).
• CAS Number
  848942-61-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₂₅ClFN₅O₃
• Molecular Weight
  473.93
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent, ATP competitive and reversible inhibitor of EGFR (ErbB-1), Neu (ErbB-2) and ErbB-3
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  11488320
• PubChem CID Link
• SMILES
  CNC(=O)CN1CCC(CC1)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC
• InChi
  InChI=1S/C23H25ClFN5O3/c1-26-21(31)12-30-8-6-14(7-9-30)33-20-10-15-18(11-19(20)32-2)27-13-28-23(15)29-17-5-3-4-16(24)22(17)25/h3-5,10-11,13-14H,6-9,12H2,1-2H3,(H,26,31)(H,27,28,29)
• InChi Key
  DFJSJLGUIXFDJP-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  AZD-8931  
• Short name
  AZD-8931
• Alternative name
  AZD-8931

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