P21 Antibody, HRP Conjugated

• Catalog number
  bs-10129R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  P21 Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  P21
• Specificity
  This is a highly specific antibody against P21.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  13-41/164
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic peptide derived from human P21
• Gene ID number
  1026
• Swiss Prot
  P38936
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  P21; CIP1; SDI1; WAF1; CAP2; CDKN1; MDA-6; p21CIP1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; CDKN1A; MDA6; PIC1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  P21   Conjugated  
• Gene symbol
  TP53COR1, TCEAL1, RPL21P26, NSG1, H3P16
• Short name
  Anti-P21
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-P21 PAb HRP
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:43652
• Gene
  TP53COR1
• Long gene name
  tumor protein p53 pathway corepressor 1
• Synonyms gene name
  • tumor protein p53 pathway corepressor 1 (non-protein coding)
• Synonyms
  • linc-p21
  • lincRNA-p21
  • Trp53cor1
• GenBank acession
  • CD515754
• Locus
  6p21.2
• Discovery year
  2015-03-25
• Entrez gene record
  102800311
• Pubmed identfication
  • 20673990
  • 22841487
  • 24381249
• Classification
  • Long non-coding RNAs with non-systematic symbols

Gene info

• Identity
  HGNC:11616
• Gene
  TCEAL1
• Long gene name
  transcription elongation factor A like 1
• Synonyms gene name
  • transcription elongation factor A (SII)-like 1
• Synonyms
  • p21
  • pp21
  • SIIR
  • P21
  • WEX9
• GenBank acession
  • M99701
• Locus
  Xq22.2
• Discovery year
  1998-09-21
• Entrez gene record
  9338
• Pubmed identfication
  • 8206389
  • 7971997
  • 16221301
• RefSeq identity
  • NM_004780
• Classification
  • Transcription elongation factor A like family
• VEGA ID
  OTTHUMG00000022699

Gene info

• Identity
  HGNC:35910
• Gene
  RPL21P26
• Long gene name
  ribosomal protein L21 pseudogene 26
• Locus
  1p22-p21
• Discovery year
  2009-03-06
• Entrez gene record
  100270882
• Pubmed identfication
  • 19123937
• RefSeq identity
  • NG_010180

Gene info

• Identity
  HGNC:18790
• Gene
  NSG1
• Long gene name
  neuronal vesicle trafficking associated 1
• Synonyms
  • P21
  • D4S234E
  • NEEP21
• Synonyms name
  • DNA segment on chromosome 4 (unique) 234 expressed sequence
  • neuron-enriched endosomal protein of 21 kD
  • neuron specific gene family member 1
• Locus
  4p16.3
• Discovery year
  2017-06-23
• Entrez gene record
  27065
• Pubmed identfication
  • 9013775
  • 16037816
  • 18299352
  • 25376768

Gene info

• Identity
  HGNC:42982
• Gene
  H3P16
• Long gene name
  H3 histone pseudogene 16
• Synonyms gene
  • H3F3AP6
• Synonyms gene name
  • H3 histone, family 3A, pseudogene 6
• Synonyms
  • p21
  • H3.6
• Locus
  4q31.1
• Discovery year
  2011-09-13
• Entrez gene record
  644914
• Pubmed identfication
  • 21782046
• RefSeq identity
  • NG_022939
• VEGA ID
  OTTHUMG00000161274

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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