FUS Antibody
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Catalog number3771-100
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PricePlease ask
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Size100 µl
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Antibody TargetFUS
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Target Alternative NameFUS, Fusion (involved in t(12;16) in malignant liposarcoma), TLS, Translocated in liposarcoma protein, Pigpen, POMp75
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse
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Immunogen SequenceSynthetic peptide of human FUS
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AccessionP35637
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Gene Id2521
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AppearanceColorless liquid
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FormLiquid
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Formulation100 µl purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
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PurificationAffinity purified
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ApplicationWestern blot, Immunoprecipitation
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Application And UsagesWestern blotting (1:500 – 1:2000) and Immunoprecipitation. HeLa cell lysate can be used as a positive control. However, the optimal concentrations should be determined individually. The antibody recognizes the FUS of human origin. Based on sequence identity, the antibody should also react with mouse samples. Reactivity to other species has not been tested.
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DescriptionFUS has been identified as a frequent translocation fusion partner of various transcription factors. FUS fusion genes have been shown to be associated with multiple tumor types which include liposarcoma, leukemia, histocytoma, and sarcoma. FUS is a multifunctional RNA-binding protein that associates with the nuclear matrix and Cajal bodies and appears to play a role in splicesome assembly, pre-mRNA splicing, DNA repair, transcriptional regulation and homologous recombination.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolFUS
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Short nameFUS Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameFUS (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameFUS RNA binding protein
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Synonyms gene
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Synonyms gene name
- fusion, derived from t(12;16) malignant liposarcoma
- amyotrophic lateral sclerosis 6
- fusion (involved in t(12;16) in malignant liposarcoma)
- fused in sarcoma
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-11-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Heterogeneous nuclear ribonucleoproteins
- Zinc fingers RANBP2-type
- RNA binding motif containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data