Bryostatin 1

  • Catalog number
    2513-10
  • Price
    Please ask
  • Size
    10 ug
  • Alternative_name
    NSC 339555; (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl 2,4-octadienoic acid ester
  • Description
    Bryostatin 1 is a naturally occurring macrocyclic lactone that binds to and activates protein kinase C, but its biological effects differ greatly from those induced by other protein kinase C activators.  More potent than phorbol myristate acetate for translocating PKCδ and ε.
  • CAS Number
    83314-01-6
  • Structure Available
    Yes
  • Peptide sequence
    No
  • Salt Form
    No
  • Molecular Formula
    C₄₇H₆₈O₁₇
  • Molecular Weight
    905.04
  • Cell Permeable
    Yes
  • Purity
    ≥98%
  • Solubilities
    DMSO (25 mg/ml) or EtOH (25 mg/ml)
  • Handling
    Protect from air and moisture
  • Tag Line
    A protein kinase C (PKC) activator
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD00893832
  • PubChem CID
    5280757
  • SMILES
    CCCC=CC=CC(=O)OC1C(=CC(=O)OC)CC2CC(OC(=O)CC(CC3CC(C(C(O3)(CC4CC(=CC(=O)OC)CC(O4)C=CC(C1(O2)O)(C)C)O)(C)C)OC(=O)C)O)C(C)O
  • InChi
    InChI=1S/C47H68O17/c1-10-11-12-13-14-15-39(51)62-43-31(22-41(53)58-9)21-34-25-37(28(2)48)61-42(54)24-32(50)23-35-26-38(59-29(3)49)45(6,7)46(55,63-35)27-36-19-30(20-40(52)57-8)18-33(60-36)16-17-44(4,5)47(43,56)64-34/h12-17,20,22,28,32-38,43,48,50,55-56H,10-11,18-19,21,23-27H2,1-9H3/b13-12+,15-14+,17-16+,30-20+,31-22+/t28-,32-,33+,34+,35-,36+,37-,38+,43+,46+,47-/m1/s1
  • InChi Key
    MJQUEDHRCUIRLF-TVIXENOKSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Bryostatin 1
  • Alternative name
    Bryostatin 1
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