Dantrolene sodium

• Catalog number
  2491-500
• Price
  Please ask
• Size
  500 mg

• Alternative_name
  1-​[[[5-​(4-​nitrophenyl)-​2-​furanyl]methylene]amino]-​2,​4-​imidazolidinedione,​ monosodium salt
• Description
  Dantrolene sodium is an inhibitor of Ca²⁺ release from sarcoplasmic reticulum via inhibition of ryanodine receptor (RYR) channels. Displays selectivity for RYR1 and RYR3 over RYR2. Acts asa skeletal muscle relaxant that depresses excitation-contraction coupling in skeletal muscle by binding to the type 1 ryanodine receptor and decreasing free intracellular calcium concentration.
• CAS Number
  14663-23-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₄H₉N₄NaO₅
• Molecular Weight
  336.23
• Cell Permeable
  No
• Purity
  ≥98%
• Solubilities
  DMSO (~ 2.5 mg/ml) or DMF (~ 12.0 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  Blocker of Ca²⁺ uptake and release from sarcoplasmic reticulum
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD00079130
• PubChem CID
  6604100
• PubChem CID Link
• SMILES
  C1C(=O)N=C(N1N=CC2=CC=C(O2)C3=CC=C(C=C3)[N+](=O)[O-])[O-].[Na+]
• InChi
  InChI=1S/C14H10N4O5.Na/c19-13-8-17(14(20)16-13)15-7-11-5-6-12(23-11)9-1-3-10(4-2-9)18(21)22;/h1-7H,8H2,(H,16,19,20);/q;+1/p-1/b15-7+;
• InChi Key
  KSRLIXGNPXAZHD-HAZZGOGXSA-M
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Dantrolene   sodium  
• Short name
  Dantrolene sodium
• Alternative name
  Dantrolene sodium

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