TNIP2 Antibody, Cy7 Conjugated

• Catalog number
  bs-7563R-Cy7
• Price
  Please ask
• Size
  0.1ml

• Long name
  TNIP2 Polyclonal Antibody, Cy7 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy7
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  TNIP2
• Specificity
  This is a highly specific antibody against TNIP2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  200-230/430
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic peptide derived from human TNIP2/ABIN2
• Gene ID number
  79155
• Swiss Prot
  Q8NFZ5
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  743nm/767nm
• Synonyms
  KLIP; ABIN2; FLIP1; TNFAIP3-interacting protein 2; A20-binding inhibitor of NF-kappa-B activation 2; ABIN-2; Fetal liver LKB1-interacting protein; TNIP2
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugated
  These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
• Additional conjugation
  Cy7
• French translation
  anticorps

• Gene target
  TNIP2   Conjugated  
• Gene symbol
  TNIP2
• Short name
  Anti-TNIP2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy7
• Alternative name
  Anti-TNIP2 PAb Cy7
• Alternative technique
  antibodies
• Alternative to gene target
  TNFAIP3 interacting protein 2, TNIP2 and IDBG-7609 and ENSG00000168884 and 79155, polyubiquitin binding, nuclei, Tnip2 and IDBG-155271 and ENSMUSG00000059866 and 231130, TNIP2 and IDBG-643700 and ENSBTAG00000015126 and 100336382

Gene info

• Identity
  HGNC:19118
• Gene
  TNIP2
• Long gene name
  TNFAIP3 interacting protein 2
• Synonyms
  • ABIN-2
  • MGC4289
  • KLIP
  • FLIP1
• GenBank acession
  • BC002740
• Locus
  4p16.3
• Discovery year
  2002-10-03
• Entrez gene record
  79155
• Pubmed identfication
  • 11390377
  • 12933576
• RefSeq identity
  • NM_024309
• VEGA ID
  OTTHUMG00000090267

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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