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Also known as
Folate Receptor alpha
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Other names
folate receptor alpha; Folate receptor alpha; folate receptor alpha; FR-alpha; KB cells FBP; OTTHUMP00000237140; OTTHUMP00000237141; OTTHUMP00000237142; OTTHUMP00000237143; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18; folate receptor 1 (adult); Adult folate-binding protein; FBP; Folate receptor 1; Folate receptor, adult; KB cells FBP; Ovarian tumor-associated antigen MOv18
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
FOLR1; FOLR1; FBP; FOLR; FOLR
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Gene name synonims
FOLR1; FOLR1; FBP; FOLR; FOLR
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Other gene names
FOLR1; FOLR1; FBP; FOLR; FOLR
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
6D398
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens), Monkey; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes membrane-bound and soluble human folate receptor (FR) alpha. Does not crossreact with mouse or rat folate receptor. Does not crossreact with the beta-isoform. Species Crossreactivity: monkey.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Highly Purified ~95% (SDS-PAGE)
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Form Appearance
Supplied as a liquid in PBS, pH 7.4. No preservatives added.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applications
ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
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Description
The Folate Receptor alpha (FRa) is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
