anti-Bax Antibody

• Catalog number
  3351
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Bax Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bax, a pro-apoptotic Bcl-2 family member, is a cytosolic protein that changes conformation and translocates to the mitochondria following apoptotic stimuli. It is thought to share significant functional homology with Bak, another pro-apoptotic Bcl-2 family member, as disruption of bax or bak has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking both show decreased apoptotic capability.
• Gene names
  Bax Antibody: BCL2L4, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4
• Antibodie s label
  unlabelled serum
• Purity
  Bax Antibody is Ion exchange chromatography purified.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  Bax antibody was made against a peptide corresponding to 16 amino acids near the amino-terminus of human Bax.
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry, immuno fluorescence, immuno precipitation
• Antibody advice
  Bax antibody can be used for detection of Bax by Western blot at 1 to 4 ug/mL. Antibody can also be used for immunocytochemistry starting at 2 ug/mL. For immunofluorescence start at 2 ug/mL.
• Suspention pH azide
  Bax Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  Bax antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  388166
• Ncbi nr
  AAA03619
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  581
• GENE symbol
  BAX
• Antigene name
  BCL2-associated X protein
• Source
  Homo sapiens
• Protein nr
  Q07812
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Bax  
• Gene symbol
  TMBIM7P, TMBIM6, TMBIM1
• Short name
  anti-Bax Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toBax (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  BCL2-associated X protein, BCL2L4, BAX and IDBG-61459 and ENSG00000087088 and 581, BH3 domain binding, nuclei, Bax and IDBG-183241 and ENSMUSG00000003873 and 12028, BAX and IDBG-640344 and ENSBTAG00000013340 and 100850136,280730

Gene info

• Identity
  HGNC:49212
• Gene
  TMBIM7P
• Long gene name
  transmembrane BAX inhibitor motif containing 7, pseudogene
• Locus
  7q21.2
• Discovery year
  2013-10-09
• Entrez gene record
  105375396
• Classification
  • Transmembrane BAX inhibitor motif containing
• VEGA ID
  OTTHUMG00000155903

Gene info

• Identity
  HGNC:11723
• Gene
  TMBIM6
• Long gene name
  transmembrane BAX inhibitor motif containing 6
• Synonyms gene
  • TEGT
• Synonyms gene name
  • testis enhanced gene transcript
• Synonyms
  • BI-1
  • BAXI1
• Synonyms name
  • BAX inhibitor 1
• GenBank acession
  • X75861
• Locus
  12q13.12
• Discovery year
  1994-08-30
• Entrez gene record
  7009
• Pubmed identfication
  • 8530040
  • 9660918
• RefSeq identity
  • NM_003217
• Classification
  • Transmembrane BAX inhibitor motif containing
• VEGA ID
  OTTHUMG00000169652

Gene info

• Identity
  HGNC:23410
• Gene
  TMBIM1
• Long gene name
  transmembrane BAX inhibitor motif containing 1
• Synonyms
  • PP1201
  • RECS1
  • LFG3
• GenBank acession
  • BN000408
• Locus
  2q35
• Discovery year
  2005-08-22
• Entrez gene record
  64114
• Pubmed identfication
  • 28481357
• RefSeq identity
  • NM_022152
• Classification
  • Transmembrane BAX inhibitor motif containing
• VEGA ID
  OTTHUMG00000133105

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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