anti- APEX1 antibody

• Catalog number
  FNab00479
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
• Immunogen
  APEX nuclease (multifunctional DNA repair enzyme) 1
• Synonyms
  APE, APE1, APEX, APX, HAP1, REF1
• Calculated MW
  Refer to figures
• Uniprot ID
  P27695
• Specificity
  Human
• Tested Application
  ELISA, WB, IP, IF
• Recommended dilution
  WB: 1:500 - 1:2000; IF: 1:50 - 1:100; IP: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human cervical cancer using FNab00479(APEX1 antibody) at dilution of 1:50
• Image4
  HepG2 cells were subjected to SDS PAGE followed by western blot with FNab00479(APEX1 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  APEX1  
• Gene symbol
  APEX1
• Short name
  anti- APEX1 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- APEX1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:587
• Gene
  APEX1
• Long gene name
  apurinic/apyrimidinic endodeoxyribonuclease 1
• Synonyms gene
  • APEX
• Synonyms gene name
  • APEX nuclease (multifunctional DNA repair enzyme)
  • APEX nuclease (multifunctional DNA repair enzyme) 1
• Synonyms
  • APE
  • REF1
  • HAP1
  • APX
  • APEN
  • REF-1
  • APE-1
• GenBank acession
  • X59764
• Locus
  14q11.2
• Discovery year
  1997-05-22
• Entrez gene record
  328
• RefSeq identity
  • NM_001641
• Classification
  • SET complex
  • Endoribonucleases
• VEGA ID
  OTTHUMG00000029544
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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