Human CellExp™ CD38, human recombinant

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• Catalog number
  P1014-50
• Price:

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• Size
  50 µg

# #

• Synonyms
  ADP-ribosyl Cyclase 1, Cyclic ADP-ribose Hydrolase 1, ADPRC 1, T11
• Alternative_names
  ADP-ribosyl Cyclase 1, Cyclic ADP-ribose Hydrolase 1, ADPRC 1, T10
• Recombinant
  Yes
• Source
  HEK 293 cells
• Purity by SDS PAGE
  ≥ 98%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 5 EU/mg
• Molecular Weight
  70 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.2um-filtered solution in PBS.
• Reconstitution Instructions
  Reconstitute in 1X PBS to the desired protein concentration.
• Background Information
  CD38, also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications including social amnesia possibly related to autism. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism, as well as some genetically determined conditions.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

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• Gene target
  CellExp™   CD38  
• Gene symbol
  CD38
• Short name
  CellExp™ CD38, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ CD38 molecule, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  CD38 molecule, ADPRC 1 and T10, CD38 and IDBG-10668 and ENSG00000004468 and 952, hydrolase activity, nuclei, Cd38 and IDBG-161475 and ENSMUSG00000029084 and 12494, CD38 and IDBG-643982 and ENSBTAG00000013569 and 327677

Gene info

• Identity
  HGNC:1667
• Gene
  CD38
• Long gene name
  CD38 molecule
• Synonyms gene name
  • CD38 antigen (p45)
• Synonyms name
  • ADP-ribosyl cyclase 1
  • NAD(+) nucleosidase
• GenBank acession
  • D84276
• Locus
  4p15.32
• Discovery year
  1986-01-01
• Entrez gene record
  952
• Pubmed identfication
  • 9074508
  • 2319135
• RefSeq identity
  • NM_001775
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000048206

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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