anti-Myelin Basic Protein Antibody, Monoclonal

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• Catalog number
  49-792
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• Size
  0.05 mg

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• Gene info
  Suitable for use in ELISA, Western Blot, Immunohistochemistry and quantification of myelin basic protein. Other applications have not been tested. Recognizes residues 130-136 in human myelin basic protein (21.5kD and 18.5kD molecular forms). Species Crossreactivity: Primate, rabbit, sheep, goat, rat and mouse. The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) found in bone marrow and the immune system may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells.
• Gene names
  MBP, Myelin A1 protein, Myelin basic protein
• Antibodie s label
  unlabelled serum
• Purity
  Protein G Column
• Ab raised in
  Mouse
• Type
  Monoclonal
• Immunoglobulin
  IgG2b
• Antigen
  Myelin Basic Protein monoclonal antibody was made against amino acids 130 - 136 of Myelin Basic Protein (Human).
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  Myelin Basic Protein antibody can be used in immunocytochemistry starting at 10 ug/mL, immunohistochemistry starting at 10 ug/mL, and flow cytometry.
• Suspention pH azide
  PBS, pH 7.4, contains no preservative.
• Keep at
  Myelin Basic Protein antibody should be stored at -20 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Goat, Human, Mouse, Primate, Rabbit, Rat, Sheep
• Omim nr
  17378805
• Ncbi nr
  P02686
• Vial with antibody
  in solution
• NCBI GENE nr
  4155
• GENE symbol
  MBP
• Antigene name
  myelin basic protein
• Source
  Homo sapiens
• Protein nr
  P02686
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Basic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

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• Gene target
  Myelin   Protein   Monoclonal  
• Short name
  anti-Myelin Protein Antibody, Monoclonal
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Alternative name
  Antibody toMyelin Basic Protein (antibody to-), monoclonal
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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