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Gefitinib for cell activation

Gefitinib for cell activation is available 2 times from Biovision labs

1589-5 | Gefitinib for cell activation size: 5 mg | 180.40 USD

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1589-25 | Gefitinib for cell activation size: 25 mg | 309.75 USD

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Supplied with N/A
Description Gefitinib was found to be a potent inhibitor of EGFR kinase (Ki = 0.40 nM), but much weaker against ErbB-2 kinase (Ki = 870 nM) and ErbB-4 kinase (Ki = 1.1 µM). The IC₅₀ values for Gefitinib to inhibit HT-29 and LoVo cell growth were 23.6 - >100 µM and 7.3 - 48.5 µM, respectively, when the exposure times are from 18 hours to 3 days. The IC₅₀ values of Gefitinib to the breast cancer cell lines BT20, HCC1937, MDA-MB-231, BT474, and SKBR3 are 15.5±1.4, 8.4±1.5, 20.7±1.1, 0.25±0.05, 0.88±0.31 µM, respectively
Category Biochemicals
Molecular formula C₂₂H₂₄ClFN₄O₃
Is it cell-permeable? Yes
Molecular weight 446.9
Storage condition -20°C
Shipping condition RT
Purification ≥99% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 184475-35-2
Storage instructions Protect from light and moisture
Maximum time for storage 24months
Physical appearance White to off-white solid
Reconstitute instructions DMSO (100 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Short name Gefitinib for activation
Technique activation
Alternative name Gefitinib to measure cellular activation
Tissue cell
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