Mirin

• Catalog number
  B1075-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  Z-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one
• Description
  Mirin is a small-molecule inhibitor of MRN (Mre11, Rad50, and Nbs1) complex. Mirin blocks the 3' and 5' exonuclease activity associated with Mre11. Prevents ATM activation in response to double strand breaks (IC₅₀ = 12 μM) and induces G2 cell cycle arrest.
• CAS Number
  1198097-97-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₀H₈N₂O₂S
• Molecular Weight
  220.25
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>20 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A small-molecule inhibitor of MRN (Mre11, Rad50, and Nbs1) complex
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  1206243
• PubChem CID Link
• SMILES
  C1=CC(=CC=C1C=C2C(=O)N=C(S2)N)O
• InChi
  InChI=1S/C10H8N2O2S/c11-10-12-9(14)8(15-10)5-6-1-3-7(13)4-2-6/h1-5,13H,(H2,11,12,14)/b8-5-
• InChi Key
  YBHQCJILTOVLHD-YVMONPNESA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Mirin  
• Short name
  Mirin
• Alternative name
  Mirin

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