D4476

• Catalog number
  1770-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl) -1H-imidazol-2-yl]benzamide
• Description
  A cell-permeable, ATP-competitive inhibitor of casein kinase 1 (CK1) (IC₅₀ = 0.3 µM). Also inhibits ALK5 (IC₅₀ = 0.5 µM) and p38ɑMAP kinase (IC₅₀ = 12 µM). Displays selectivity over many other protein kinases.
• CAS Number
  301836-43-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₁₈N₄O₃
• Molecular Weight
  398.41
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (100 mM)
• Handling
  Protect from air and light
• Tag Line
  A casein kinase (CK) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD09037526
• PubChem CID
  6419753
• PubChem CID Link
• SMILES
  C1COC2=C(O1)C=CC(=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
• InChi
  InChI=1S/C23H18N4O3/c24-22(28)14-4-6-15(7-5-14)23-26-20(21(27-23)17-3-1-2-10-25-17)16-8-9-18-19(13-16)30-12-11-29-18/h1-10,13H,11-12H2,(H2,24,28)(H,26,27)
• InChi Key
  DPDZHVCKYBCJHW-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  D4476  
• Short name
  D4476
• Alternative name
  D4476

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