7BIO

• Catalog number
  9690-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  7-Bromoindirubin-3'-oxime
• Description
  7BIO is a caspase- independent nonapoptotic cell death inducer. Also acts as an ATP-competitive FLT3 inhibitor and DYRK1A and DYRK 2 (Dual-specificity tyrosine phosphorylation-regulated kinase) inhibitor. In addition, 7BIO is a necrosis inducer and inflammasome activator. Also a potent inhibitor of Aurora kinase B and C.
• CAS Number
  916440-85-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₆H₁₀BrN₃O₂
• Molecular Weight
  356.2
• Cell Permeable
  Yes
• Purity
  ≥98% by NMR
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A caspase- independent nonapoptotic cell death inducer and an inflammasome activator
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  11846148
• PubChem CID Link
• SMILES
  C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=C(C4=NC3=O)Br)NO
• InChi
  InChI=1S/C16H10BrN3O2/c17-10-6-3-5-9-12(16(21)19-13(9)10)15-14(20-22)8-4-1-2-7-11(8)18-15/h1-7,18,20,22H
• InChi Key
  MGVCNALPOHOEQM-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  7BIO  
• Short name
  7BIO
• Alternative name
  7BIO

Product images

Similar products