PHT-427

• Catalog number
  2465-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  4-Dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide
• Description
  A potent Akt and PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) inhibitor. PH 427 binds to the pleckstrin homology (PH) domain of Akt and PDPK1 signaling with significant in vivo antitumor activity and minimal toxicity.
• CAS Number
  1191951-57-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₀H₃₁N₃O₃S₂
• Molecular Weight
  409.61
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (> 80 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent Akt and PDPK1 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• PubChem CID
  44240850
• PubChem CID Link
• SMILES
  CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2
• InChi
  InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)
• InChi Key
  BYWWNRBKPCPJMG-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  PHT-427  
• Short name
  PHT-427
• Alternative name
  PHT-427

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