Bexarotene
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Catalog number1575-5
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PricePlease ask
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Size5 mg
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Alternative_nameTargretin, LGD-1069, LG-1069, LG10069, SR-11247
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DescriptionBexarotene is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas. The receptor-selective retinoids might be particularly useful in preventing ER-negative breast cancer.
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CAS Number153559-49-0
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₄H₂₈O₂
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Molecular Weight348.48
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Cell PermeableYes
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Purity≥99%
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SolubilitiesDMSO
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HandlingProtect from light and air
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Tag LineAn antineoplastic agent
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24months
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MDL NumberMFCD00932428
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PubChem CID82146
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SMILESCC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
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InChiInChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)
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InChi KeyNAVMQTYZDKMPEU-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameBexarotene
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Alternative nameBexarotene
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