Bexarotene

  • Catalog number
    1575-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    Targretin, LGD-1069, LG-1069, LG10069, SR-11247
  • Description
    Bexarotene is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids.  It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas. The receptor-selective retinoids might be particularly useful in preventing ER-negative breast cancer.
  • CAS Number
    153559-49-0
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₄H₂₈O₂
  • Molecular Weight
    348.48
  • Cell Permeable
    Yes
  • Purity
    ≥99%
  • Solubilities
    DMSO
  • Handling
    Protect from light and air
  • Tag Line
    An antineoplastic agent
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24months
  • MDL Number
    MFCD00932428
  • PubChem CID
    82146
  • SMILES
    CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
  • InChi
    InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)
  • InChi Key
    NAVMQTYZDKMPEU-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Bexarotene
  • Alternative name
    Bexarotene
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