HCG-beta

• Catalog number
  GEN438422
• Price
  Please ask
• Size
  100ug

• Also known as
  HCG-beta
• Other names
  choriogonadotropin subunit beta; Choriogonadotropin subunit beta; choriogonadotropin subunit beta; CG-beta; chorionic gonadotropin beta chain; chorionic gonadotrophin chain beta; chorionic gonadotropin beta subunit; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin, beta polypeptide; Chorionic gonadotrophin chain beta
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CGB
• Gene name synonims
  N/A
• Other gene names
  CGB; CGB; CGB3; CGB5; CGB7; CGB8; hCGB; CGB3; CG-beta
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1 + IgG1
• Clone
  HCGb/54+ HCGb/459
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  Western Blot (WB), Immunohistology (IH)

• Gene target
  HCG-beta  
• Gene symbol
  CGB5, UBL3, PPP1R11, CGA
• Short name
  HCG-beta
• Alternative name
  Anti-HCG-beta

Gene info

• Identity
  HGNC:16452
• Gene
  CGB5
• Long gene name
  chorionic gonadotropin subunit beta 5
• Synonyms gene name
  • chorionic gonadotropin, beta polypeptide 5
  • chorionic gonadotropin beta subunit 5
• Synonyms
  • HCG
• GenBank acession
  • X00265
• Locus
  19q13.33
• Discovery year
  2001-12-05
• Entrez gene record
  93659
• Pubmed identfication
  • 6194155
• RefSeq identity
  • NM_033043
• Classification
  • Glycoprotein hormone subunits
• VEGA ID
  OTTHUMG00000183337

Gene info

• Identity
  HGNC:12504
• Gene
  UBL3
• Long gene name
  ubiquitin like 3
• Synonyms gene
  • PNSC1
• Synonyms gene name
  • ubiquitin-like 3
• Synonyms
  • HCG-1
  • DKFZP434K151
  • FLJ32018
• GenBank acession
  • AF044221
• Locus
  13q12.3
• Discovery year
  1998-01-30
• Entrez gene record
  5412
• Pubmed identfication
  • 10375635
• RefSeq identity
  • NM_007106
• VEGA ID
  OTTHUMG00000016661

Gene info

• Identity
  HGNC:9285
• Gene
  PPP1R11
• Long gene name
  protein phosphatase 1 regulatory inhibitor subunit 11
• Synonyms gene
  • TCTE5
• Synonyms gene name
  • protein phosphatase 1, regulatory (inhibitor) subunit 11
• Synonyms
  • HCGV
  • Tctex5
  • HCG-V
  • CFAP255
• GenBank acession
  • X81003
• Locus
  6p22.1
• Discovery year
  2000-02-11
• Entrez gene record
  6992
• Pubmed identfication
  • 9843442
  • 8781118
• RefSeq identity
  • NM_021959
• Classification
  • Protein phosphatase 1 regulatory subunits
  • Cilia and flagella associated
• VEGA ID
  OTTHUMG00000031260

Gene info

• Identity
  HGNC:1885
• Gene
  CGA
• Long gene name
  glycoprotein hormones, alpha polypeptide
• Synonyms
  • HCG
  • GPHa
  • GPHA1
  • FSHA
  • LHA
  • TSHA
  • GPA1
• Synonyms name
  • follicle-stimulating hormone alpha subunit
  • chorionic gonadotropin, alpha polypeptide
  • luteinizing hormone alpha chain
  • lutropin alpha chain
  • thyroid-stimulating hormone alpha chain
  • glycoprotein hormones alpha chain
• GenBank acession
  • V00518
• Locus
  6q14.3
• Discovery year
  1986-01-01
• Entrez gene record
  1081
• Pubmed identfication
  • 6286817
• RefSeq identity
  • NM_000735
• Classification
  • Receptor ligands
  • Glycoprotein hormone subunits
• VEGA ID
  OTTHUMG00000015161

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