NECA

  • Catalog number
    B2262-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide; 5'-N-Ethylcarboxamidoadenosine
  • Description
    NECA is a high affinity adenosine receptor agonist (Ki values are 6.2, 14, and 20 nM for human A3, A1 and A2A receptors respectively; EC₅₀ = 2.4 μM for human A2B). NECA is also reported to act as a potent vasodilator and can inhibit platelet aggregation by increasing cAMP (EC₅₀ = 3.1 µM).
  • CAS Number
    35920-39-9
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₂H₁₆N₆O₄
  • Molecular Weight
    308.3
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>10 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A high affinity adenosine receptor agonist
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00069195
  • PubChem CID
    448222
  • SMILES
    CCNC(=O)C1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O
  • InChi
    InChI=1S/C12H16N6O4/c1-2-14-11(21)8-6(19)7(20)12(22-8)18-4-17-5-9(13)15-3-16-10(5)18/h3-4,6-8,12,19-20H,2H2,1H3,(H,14,21)(H2,13,15,16)/t6-,7+,8-,12+/m0/s1
  • InChi Key
    JADDQZYHOWSFJD-FLNNQWSLSA-N
  • MSDS Available
    YES
  • Gene target
    NECA  
  • Short name
    NECA
  • Alternative name
    NECA
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