Bafilomycin A1

• Catalog number
  1829-250
• Price
  Please ask
• Size
  250 ug

• Description
  A highly potent and selective inhibitor of vacuolar H+-ATPases (V-ATPases) in vitro. It is effective in nanomolar concentrations in animal cells, plant cells and microorganisms; also selective over other ATP hydrolyzing enzymes such as F-ATPases, Ca2+-ATPases, Na+/K+-ATPases and plasma membrane H+-ATPases. Also prevents autophagy at a late stage by inhibiting fusion between autophagosomes and lysosomes.
• CAS Number
  88899-55-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₃₅H₅₈O₉
• Molecular Weight
  622.84
• Cell Permeable
  Yes
• Purity
  ≥95% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  An inhibitor of vacuolar H⁺-ATPases (V-ATPases)
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD06795130
• PubChem CID
  53321987
• PubChem CID Link
• SMILES
  CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)O)O)O)OC)C
• InChi
  InChI=1S/C35H58O9/c1-19(2)32-24(7)27(36)18-35(40,44-32)26(9)31(38)25(8)33-28(41-10)14-12-13-20(3)15-22(5)30(37)23(6)16-21(4)17-29(42-11)34(39)43-33/h12-14,16-17,19,22-28,30-33,36-38,40H,15,18H2,1-11H3/b14-12-,20-13+,21-16+,29-17-/t22-,23+,24-,25-,26-,27+,28-,30-,31+,32+,33?,35+/m0/s1
• InChi Key
  XDHNQDDQEHDUTM-MKFMMVOISA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Bafilomycin  
• Short name
  Bafilomycin A1
• Alternative name
  Bafilomycin A1

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