Anti-STAT3 Antibody

• Catalog number
  A1670-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  STAT3
• Target Alternative Name
  Signal transducer and activator of transcription 3, stat -3, STAT3, STAT -3, STAT 3, APRF , FLJ20882 , mgC16063
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, Mouse, Rat
• Immunogen Sequence
  A synthesized peptide derived from human STAT3
• Accession
  P40763
• Gene Id
  6774
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  In phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol
• Purification
  Affinity purified
• Application
  WB,IHC, ICC/IF, ELISA
• Positive Control
  WB: K562 cell lysates, IF/ICC: LOVE cells, IHC: pancreas tissue
• Application And Usages
  WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA (peptide) 1:20000-1:40000
• Description
  Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Althoμgh early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  STAT3  
• Gene symbol
  STAT3
• Short name
  Anti-STAT3 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toSTAT3 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  signal transducer and activator of transcription 3 (acute-phase response factor), ADMIO and APRF and HIES, STAT3 and IDBG-50702 and ENSG00000168610 and 6774, protein dimerization activity, nuclei, Stat3 and IDBG-211637 and ENSMUSG00000004040 and 20848, STAT3 and IDBG-640197 and ENSBTAG00000021523 and 101910056,508541

Gene info

• Identity
  HGNC:11364
• Gene
  STAT3
• Long gene name
  signal transducer and activator of transcription 3
• Synonyms gene name
  • signal transducer and activator of transcription 3 (acute-phase response factor)
• Synonyms
  • APRF
• GenBank acession
  • BC014482
• Locus
  17q21.2
• Discovery year
  1995-11-08
• Entrez gene record
  6774
• Pubmed identfication
  • 7512451
• RefSeq identity
  • NM_139276
  • NM_003150
• Classification
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000150645
• Locus Specific Databases
  • STAT3base: Mutation registry for Hyper-IgE syndrome
  • LRG_112

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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