TRAIL/APO 2 Ligand

• Catalog number
  PR27058
• Price
  Please ask
• Size
  50 ug

• Dilutions
  NA
• Immunogen
  NA
• Storage
  Store at room temperature for up to 3 weeks. Store desiccated at -20°C. Avoid freeze-thaw cycles.
• Storage Location
  Ambient
• Entrez
  NA
• UniProt
  NA
• RRID
  NA
• Applications
  NA
• Types
  Protein
• Format A
  NA
• Format B
  lyophilized
• Datasheets
• Description
  FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

• Gene target
  TRAIL/APO   Ligand  
• Gene symbol
  TNFSF10, FAS, AOPEP, TNFRSF10B, TNFRSF25
• Short name
  TRAIL/APO 2 Ligand
• Species
  Human
• Alternative name
  TRAIL/APO 2 Ligand

Gene info

• Identity
  HGNC:11925
• Gene
  TNFSF10
• Long gene name
  TNF superfamily member 10
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 10
• Synonyms
  • TRAIL
  • Apo-2L
  • TL2
  • CD253
• GenBank acession
  • U37518
• Locus
  3q26
• Discovery year
  1998-12-04
• Pubmed identfication
  • 8777713
  • 8663110
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000156917

Gene info

• Identity
  HGNC:11920
• Gene
  FAS
• Long gene name
  Fas cell surface death receptor
• Synonyms gene
  • FAS1
  • APT1
  • TNFRSF6
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 6
  • Fas (TNF receptor superfamily, member 6)
• Synonyms
  • CD95
  • APO-1
• Synonyms name
  • TNF receptor superfamily member 6
• GenBank acession
  • M67454
• Locus
  10q23.31
• Discovery year
  1992-06-25
• Entrez gene record
  355
• Pubmed identfication
  • 1385299
  • 1385309
• Classification
  • Tumor necrosis factor receptor superfamily
  • Death inducing signaling complex
  • CD molecules
• VEGA ID
  OTTHUMG00000018701
• Locus Specific Databases
  • Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS
  • LOVD at NCBI
  • LRG_134

Gene info

• Identity
  HGNC:1361
• Gene
  AOPEP
• Long gene name
  aminopeptidase O (putative)
• Synonyms gene
  • C9orf3
• Synonyms gene name
  • chromosome 9 open reading frame 3
• Synonyms
  • C90RF3
  • FLJ14675
  • APO
  • AP-O
• Synonyms name
  • aminopeptidase O
• GenBank acession
  • AF043896
• Locus
  9q22.32
• Discovery year
  1999-01-28
• Entrez gene record
  84909
• Pubmed identfication
  • 15687497
• RefSeq identity
  • NM_032823
• Classification
  • M1 metallopeptidases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000020276

Gene info

• Identity
  HGNC:11905
• Gene
  TNFRSF10B
• Long gene name
  TNF receptor superfamily member 10b
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 10b
• Synonyms
  • DR5
  • KILLER
  • TRICK2A
  • TRAIL-R2
  • TRICKB
  • CD262
  • TRAILR2
• GenBank acession
  • AF012628
• Locus
  8p21.3
• Discovery year
  1998-12-04
• Entrez gene record
  8795
• Pubmed identfication
  • 9285725
  • 9311998
• RefSeq identity
  • NM_147187
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000097826

Gene info

• Identity
  HGNC:11910
• Gene
  TNFRSF25
• Long gene name
  TNF receptor superfamily member 25
• Synonyms gene
  • TNFRSF12
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
  • tumor necrosis factor receptor superfamily, member 25
• Synonyms
  • DR3
  • TRAMP
  • WSL-1
  • LARD
  • WSL-LR
  • DDR3
  • TR3
  • APO-3
• GenBank acession
  • U72763
• Locus
  1p36.31
• Discovery year
  1998-12-04
• Entrez gene record
  8718
• Pubmed identfication
  • 9052839
  • 8934525
• RefSeq identity
  • NM_148965
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000000831

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