Produced against a synthetic peptide mapped to the C-terminal tail (amino acids 911-929) of rat UT-A1 (antibody designation L194)
Antibody's full description
Rabbit Anti-Rat UT-A1 Polyclonal
Primary research fields
Neuroscience, Pumps/Transporters, Urea Transporters
Antibody's other name
SLC14A2 Antibody, FLJ16167 Antibody, hUT-A6 Antibody, HUT2 Antibody, kidney Antibody, MGC119566 Antibody, MGC119567 Antibody, Slc14a2 Antibody, Solute carrier family 14 (urea transporter) Antibody, member 2 Antibody, Solute carrier family 14 member 2 Antibody, Urea transporter 2 Antibody, Urea transporter Antibody, Urea transporter kidney Antibody, UT-A2 Antibody, UT2 Antibody, UT2_HUMAN Antibody, UTA Antibody, UTR Antibody, UT1 Antibody, UTA1 Antibody
Antibody's recommended dilutions for use
WB (1:1000); optimal dilutions for assays should be determined by the user.
Antibody's purified from
Protein A Purified
Recommended buffer for storage
PBS, 50% glycerol, 0.09% sodium azide
Detects ~97 and 127kDa.
Blue Ice or 4°C
Certificate of analysis
1 µg/ml of SPC-406 was sufficient for detection of UT-A1 in 20 µg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
Antibody in cell
Cell Membrane, Apical Cell Membrane
See included datasheet or contact our support service.
UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates trans-epithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promoter and expressed in the thin descending limb of Henle, viz. UT-A2) (1, 2).
1. Nielsen S., et al. (1996) Proc Natl Acad Sci U S A. 93(11): 5495-500. 2. Smith C.P. (2009) Exp Physiol. 94(2): 180-185.
Refer to PubMed
To be tested
To be tested
Contact our support service to receive datasheet or other technical documentation.
Representative figure legend
Western blot analysis of Rat Inner medulla showing detection of UT-A1 protein using Rabbit Anti-UT-A1 Polyclonal Antibody (SPC-406). Primary Antibody: Rabbit Anti-UT-A1 Polyclonal Antibody (SPC-406) at 1:1000. Rabbit Anti-UT-A1 Antibody used in Western blot (WB) on Rat Inner medulla (SPC-406)
Country of production
Total weight (kg)
No similar products groups has been found