MK-1775

• Catalog number
  HY-10993
• Price
  Please ask
• Size
  2X10mM/1mL

• Alternative_Names
  AZD1775;Adavosertib
• CAS
  955365-80-7
• MWt
  500.60
• Formula
  C27H32N8O2
• Solubility
  10 mM in DMSO
• Clinical_Information
  Phase 2
• Pathway
  Cell Cycle/DNA Damage
• Target
  Wee1
• Datasheet
• SDS

• Gene target
  MK-1775  
• Gene symbol
  MVK, STYXL1, MDK, MAPKAPK3, EPCAM
• Short name
  MK-1775
• Alternative name
  MK-1775

Gene info

• Identity
  HGNC:7530
• Gene
  MVK
• Long gene name
  mevalonate kinase
• Synonyms gene name
  • mevalonate kinase (mevalonic aciduria)
• Synonyms
  • LRBP
  • MK
• Synonyms name
  • LH receptor mRNA-binding protein
  • mevalonic aciduria
• GenBank acession
  • M88468
• Locus
  12q24.11
• Discovery year
  1992-10-06
• Entrez gene record
  4598
• Pubmed identfication
  • 1377680
• RefSeq identity
  • NM_000431
• VEGA ID
  OTTHUMG00000169256
• Locus Specific Databases
  • INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
  • LRG_156

Gene info

• Identity
  HGNC:18165
• Gene
  STYXL1
• Long gene name
  serine/threonine/tyrosine interacting like 1
• Synonyms gene
  • DUSP24
• Synonyms gene name
  • dual specificity phosphatase 24 (putative)
• Synonyms
  • MK-STYX
• GenBank acession
  • AF069762
• Locus
  7q11.23
• Discovery year
  2005-01-20
• Entrez gene record
  51657
• Pubmed identfication
  • 9757831
• RefSeq identity
  • NM_016086
• Classification
  • MAP kinase phosphatases
• VEGA ID
  OTTHUMG00000130459

Gene info

• Identity
  HGNC:6972
• Gene
  MDK
• Long gene name
  midkine
• Synonyms gene
  • NEGF2
• Synonyms gene name
  • neurite growth-promoting factor 2
• Synonyms
  • MK
  • FLJ27379
• Locus
  11p11.2
• Discovery year
  1991-07-10
• Entrez gene record
  4192
• Pubmed identfication
  • 8406506
• RefSeq identity
  • NM_001012334
• VEGA ID
  OTTHUMG00000150315

Gene info

• Identity
  HGNC:6888
• Gene
  MAPKAPK3
• Long gene name
  MAPK activated protein kinase 3
• Synonyms gene name
  • mitogen-activated protein kinase-activated protein kinase 3
• Synonyms
  • 3pK
  • MAPKAP3
  • 3PK
  • MK-3
  • MK3
• GenBank acession
  • U43784
• Locus
  3p21.2
• Discovery year
  1999-03-26
• Entrez gene record
  7867
• Pubmed identfication
  • 8626550
  • 8622688
• RefSeq identity
  • NM_004635
• Classification
  • MAPK activated protein kinases
• VEGA ID
  OTTHUMG00000156850

Gene info

• Identity
  HGNC:11529
• Gene
  EPCAM
• Long gene name
  epithelial cell adhesion molecule
• Synonyms gene
  • M4S1
  • MIC18
  • TACSTD1
• Synonyms gene name
  • antigen identified by monoclonal antibody AUA1
  • tumor-associated calcium signal transducer 1
• Synonyms
  • Ly74
  • TROP1
  • GA733-2
  • EGP34
  • EGP40
  • EGP-2
  • KSA
  • CD326
  • Ep-CAM
  • HEA125
  • KS1/4
  • MK-1
  • MH99
  • MOC31
  • MOC-31
  • 323/A3
  • 17-1A
  • TACST-1
  • CO-17A
  • ESA
  • BerEp4
  • Ber-Ep4
• Synonyms name
  • trophoblast cell surface antigen 1
• GenBank acession
  • M33011
• Locus
  2p21
• Discovery year
  1995-10-02
• Entrez gene record
  4072
• Pubmed identfication
  • 8382772
  • 11306819
• Classification
  • MicroRNA protein coding host genes
  • CD molecules
• VEGA ID
  OTTHUMG00000128853
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_215

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