anti-NOX4 Antibody

• Catalog number
  7927
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX4 is is expressed in multiple tissues and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) (2,3). Unlike other NOX proteins, NOX4 does not require cytosolic subunits and thus is constitutively active (4). The function of NOX4 remains unclear as it plays both protective and deleterious roles in cellular metabolism.
• Gene names
  NAPDH oxidase 4, NOX-4, RENOX, KOX, KOX-1
• Antibodie s label
  unlabelled serum
• Purity
  NOX4 antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  NOX4 antibody is human, mouse, and rat reactive. At least four isoforms of NOX4 are known to exist. NOX4 is predicted to not cross-react with other NOX proteins.
• Antigen
  NOX4 antibody was made against a 14 amino acid peptide near the amino terminus of human NOX4.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  NOX4 antibody can be used for detection of NOX4 by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  NOX4 antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  NOX4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  8393843
• Ncbi nr
  NP_058627
• KDa
  Predicted: 64 kDa Observed: 68 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  50507
• GENE symbol
  NOX4
• Antigene name
  NADPH oxidase 4
• Source
  homo sapiens
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NOX4  
• Gene symbol
  NOX4
• Short name
  anti-NOX4 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toNOX4 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7891
• Gene
  NOX4
• Long gene name
  NADPH oxidase 4
• Synonyms
  • KOX-1
  • KOX
• GenBank acession
  • AF254621
• Locus
  11q14.3
• Discovery year
  2000-05-30
• Entrez gene record
  50507
• RefSeq identity
  • NM_016931
• VEGA ID
  OTTHUMG00000167298

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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