VU0361737

• Catalog number
  9418-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide
• Description
  VU 0361737 is a selective, brain-permeable, positive allosteric modulator at mGlu4 receptors (EC₅₀ values are 240 and 110 nM at human and rat receptors respectively). Inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors and displays weak activity at mGlu5 and mGlu8 receptors.
• CAS Number
  1161205-04-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₃H₁₁ClN₂O₂
• Molecular Weight
  262.69
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>20 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A positive allosteric modulator at mGlu4 receptors
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  44191096
• PubChem CID Link
• SMILES
  COC1=C(C=CC(=C1)NC(=O)C2=CC=CC=N2)Cl
• InChi
  InChI=1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
• InChi Key
  ARYUXFNGXHNNDM-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  VU0361737  
• Short name
  VU0361737
• Alternative name
  VU0361737

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