CCF-642

  • Catalog number
    B2009-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    3-(4-Methoxyphenyl)-5-[(5-nitro-2-thienyl)methylene]-2-thioxo-4-thiazolidinone
  • Description
    CCF-642 is a protein disulfide isomerase (PDI) inhibitor that displays anticancer activity in multiple myeloma. Consistent with PDI inhibition, CCF642 causes acute ER stress in multiple myeloma cells accompanied by apoptosis-inducing calcium release. 
  • CAS Number
    346640-08-2 
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₅H₁₀N₂O₄S₃ 
  • Molecular Weight
    378.44
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A protein disulfide isomerase (PDI) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    2901297
  • SMILES
    COC1=CC=C(C=C1)N2C(=O)C(=CC3=CC=C(S3)[N+](=O)[O-])SC2=S
  • InChi
    InChI=1S/C15H10N2O4S3/c1-21-10-4-2-9(3-5-10)16-14(18)12(24-15(16)22)8-11-6-7-13(23-11)17(19)20/h2-8H,1H3
  • InChi Key
    SPYIETQLOVDJCF-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    CCF-642  
  • Gene symbol
    MIR642A
  • Short name
    CCF-642
  • Alternative name
    CCF-642
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